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This study aims to systematically profile membrane protein alterations associated with chondrocyte senescence, in order to identify surface markers specifically upregulated in aged cartilage. We established two in vitro models by treating primary chondrocytes with IL-1β or bleomycin, and one in vivo...
ORGANISM(S): Mus Musculus 
2025-06-10 | PXD064867 |
MSCs were lysed in cell lysis buffer for Western blotting and IP (Beyotime, Cat. No. P0013). A Dynabeads™ protein G immunoprecipitation kit (Invitrogen, Cat. No. 10007D) was used for Co-IP according to the manufacturer’s instructions. Dynabeads were resuspended and placed on a magnet to remove the s...
ORGANISM(S): Homo Sapiens 
2022-06-16 | PXD034615 |
This project aims to identify the specific proteins interacting with lncRNA SNHG9 in hepatoma cells. We performed RNA pull-down assays using biotin-labeled SNHG9 probes in Huh7 cell lysates, followed by mass spectrometry (LC-MS/MS) to analyze the pulled-down protein.
ORGANISM(S): Homo Sapiens 
2026-04-20 | PXD077375 |
Lysine acetylation (Kac) as an important post-translational modification of histone is essential for gene expression regulation in hepatocellular carcinoma (HCC), however the atlas of whole acetylated proteins for HCC tissue and the difference of protein acetylation between human normal and HCC tiss...
ORGANISM(S): Homo Sapiens 
2020-10-24 | PXD022161 |
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