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Circadian dysregulation associates with numerous diseases including metabolic dysfunction, sleep disorder, depression and aging. Given that declined circadian amplitude is a trait commonly found with compromised health, interventions that design in precluding circadian amplitude from dampening will ...
ORGANISM(S): Mus <genus> 
Telomere homeostasis, crucial for various biological processes, relies on telomerase activity. We identified ZC3H15 as a novel telomerase-interacting protein. Its deletion unexpectedly increased telomerase activity but led to shortened telomeres and cellular senescence. ZC3H15 interacts with telomer...
ORGANISM(S): Homo Sapiens 
proteomics profiling analysis of three different chemo-sensitive and -resistant HNSCC patients derived CAFs.
ORGANISM(S): Homo Sapiens 
2022-11-23 | PXD038343 |
The COVID-19 pandemic is spreading globally with high disparity in the susceptibility of the disease severity. Identification of the key underlying factors for this disparity is highly warranted. Here we describe constructing a proteomic risk score based on 20 blood proteomic biomarkers which predic...
ORGANISM(S): Homo Sapiens 
2020-06-09 | PXD019675 |
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