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In this study, we aimed to identify potential metabolic biomarkers that can improve the diagnostic accuracy of sepsis. Sixty-six patients including 30 septic and 36 nonsepsis patients from an intensive care unit were recruited. The global plasma and urine metabolomic profiles were determined by ultr...
2023-04-18 | MTBLS3505 | MetaboLights
The possibility of lung regeneration has been long discounted due to the irreversible nature of chronic lung diseases. However, patients who sustain massive loss of lung tissue during acute infections often recover full pulmonary function. Correspondingly, we previously demonstrated lung regenerat...
ORGANISM(S): Mus musculus 
The possibility of lung regeneration has been long discounted due to the irreversible nature of chronic lung diseases. However, patients who sustain massive loss of lung tissue during acute infections often recover full pulmonary function. Correspondingly, we previously demonstrated lung regenerat...
ORGANISM(S): Mus musculus 
Purpose:The purpose of this study is to create unbiased, stage-specific transcriptomes by RNA-seq analyses of pure populations of both murine and human erythroblasts at distinct developmental stages. Methods: Recently developed FACS-based methods (Chen et al, PNAS, Liu et al, Blood, Hu et al Blood) ...
ORGANISM(S): Mus musculus 
Immune checkpoint inhibitor (ICI) therapies revitalize anti-cancer responses by intercepting protein-protein interactions between exhausted CD8 T (Tex) cells and cancer cells (e.g. PD-1:PD-L1). However, up to 50% of patients receiving ICIs relapse, warranting further interrogation of the underpinnin...
ORGANISM(S): Mus musculus (Mouse) 
2025-04-25 | PXD052688 | Pride
Expression profiling of distinct central nervous system (CNS) cell populations has been employed to facilitate disease classification and to provide insights into the molecular basis of brain pathology. One important cell type implicated in a wide variety of CNS disease states is the resident brain ...
ORGANISM(S): Mus musculus 
'Florigen', encoded by FT genes, is synthesized in leaves and transported to the shoot apical meristem (SAM) to induce flower development. At the SAM, 14-3-3 proteins are proposed to act as receptors for FT and to mediate the indirect interaction between FT and the bZIP transcription factor FD to fo...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-09-02 | PXD067955 | Pride
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