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MetabolomicsSerum protein N-glycosylation changes in multiple myeloma

BACKGROUND: Multiple myeloma is characterized by clonal proliferation of malignant plasma cells in the bone marrow that produce monoclonal immunoglobulins. N-glycosylation changes of these monoclonal immunoglobulins have been reported in multiple myeloma, but previous studies on...

2022-04-27 | MTBLS676 | MetaboLights
ProteomicsProfiling the Proteoforms of Urinary Prostate-Specific Antigen by Capillary Electrophoresis - Mass Spectrometry
This data set contains all raw data files in the mzXML format that belongs to the manuscript: Profiling the Proteoforms of Urinary Prostate Specific Antigen by Capillary Electrophoresis Mass Spectrometry, by Alan B. Moran, Elena Dominguez Vega, Jan Nouta, Tamas Pongracz, Theo M. de Reijke, Manfred W...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-01-15 | MSV000086699 | MassIVE
ProteomicsProfiling the Proteoforms of Urinary Prostate-Specific Antigen by Capillary Electrophoresis - Mass Spectrometry
This data set contains all raw data files in the mzXML format that belongs to the manuscript: Profiling the Proteoforms of Urinary Prostate Specific Antigen by Capillary Electrophoresis Mass Spectrometry, by Alan B. Moran, Elena Dominguez Vega, Jan Nouta, Tamas Pongracz, Theo M. de Reijke, Manfred W...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-01-18 | MSV000086715 | MassIVE
MetabolomicsN-glycosylation Profiling of Colorectal Cancer Cell Lines Reveals Association of Fucosylation with Differentiation and Caudal Type Homebox 1 (CDX1)/Villin mRNA Expression
Various cancers such as colorectal cancer (CRC) are associated with alterations in protein glycosylation. CRC cell lines are frequently used to study these (glyco)biological changes and their mechanisms. However, differences between CRC cell lines with regard to their glycosylation have hitherto bee...
2017-02-03 | MTBLS227 | MetaboLights
ProteomicsCompetition or indifference: Neutron-Encoding to profile linkage selectivity of deubiquitinating enzymes
This data set contains all raw data files in the mzXML (for LC-MS data) format that belongs to the manuscript "Competition or indifference: Neutron-Encoding to profile linkage selectivity of deubiquitinating enzymes" by Bianca D. M. van Tol, Bjorn R. van Doodewaerd, Guinevere S. M. Lageveen-Kammeije...
ORGANISM(S): Synthetic Ubiquitins 
2022-10-05 | MSV000090455 | MassIVE
ProteomicsIgA deglycosylation to identify glycosylation sites
In order to provide information on the peptide sequence of the IgA glycopeptides, a proteomics analysis was run on LC-MS/MS data of N-glycosidase F-digested IgA samples, in which the N-glycans had been released. The samples included IgA (isolated) from: 1) the saliva samples from two healthy donors,...
ORGANISM(S): Homo sapiens (Human) 
2018-11-09 | PXD011228 | Pride
Iga Secretory iga Plasma Colostrum Saliva 
ProteomicsMiddle-up analysis of polyclonal IgG-Fc
Middle-up strategy for the analysis of the fragment crystallizable (Fc) region of human plasma immunoglobulins G (IgGs). The use of hydrophilic interaction liquid chromatography (HILIC) and capillary electrophoresis (CE) coupled to mass spectrometry (MS) allowed to get a comprenhesive view of the N-...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-05-08 | MSV000085388 | MassIVE
ProteomicsSupporting information for tryptic EPO glycopeptide LC-MS analysis via cysteine aminoethylation
Supplementary information for a technical note describing the application of cysteine aminoethylation for the site-specific glycosylation analysis of recombinant human EPO using trypsin as sole protease.
ORGANISM(S): Cho Cells 
2020-04-21 | MSV000085318 | MassIVE
ProteomicsAntigen-specific IgG Glycosylation Profiles in Hamsters and Macaques Following COVID-19 Vaccination
Vaccination triggers the production of antigen-specific antibodies, including IgG. IgG molecules are glycosylated at the Fc region, and these glycan modifications markedly influence Fc receptor binding and downstream immune functions. Notably, infections with enveloped viruses such as SARS-CoV-2 can...
ORGANISM(S): Mesocricetus auratus (Golden hamster) Macaca mulatta (Rhesus macaque) 
2026-03-11 | PXD068257 | Pride
Glycosylation Antibody Sars-cov-2 Vaccination Covid-19 
ProteomicsIntegrated glycomic and proteomic signatures of butyrate-stimulated colorectal cancer cell line differentiation
It was previously observed that changes in the expression of specific proteins as well as protein glycosylation occur with differentiation. In this study, specific mucin O-glycans were identified that mark butyrate-induced epithelial differentiation of the intestinal cell line CaCo-2, by applying po...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD037450 | Pride
Caco-2 Differentiation 
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