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Hyperuricemia (HUA), primarily driven by xanthine oxidase (XO)-mediated uric acid production, presents substantial challenges to both human health and livestock productivity. While conventional XO inhibitors are effective in mitigating HUA, they are often linked to severe adverse effects. In this st...
2026-04-29 | MTBLS14398 | MetaboLights

Tea anthracnose caused by Glomerella cingulata threatens yield and quality, while resistance to legacy fungicides highlights the need for new modes of action. We characterized the antifungal activity and mechanism of bifemetstrobin against G. cingulata by combining efficacy assays with cell ...

2026-03-13 | MTBLS13992 | MetaboLights

Hyperuricemia (HUA) has emerged as an increasingly prevalent metabolic disorder worldwide. This study aimed to investigate the effects of red kidney bean (Phaseolus vulgaris L.) anthocyanins (RKBA) on alleviating HUA and screen the lead candidate. RKBA effectively inhibited XOD in vitro. In vivo ...

2025-10-29 | MTBLS13234 | MetaboLights
Xanthine oxidase-lactoperoxidase system: Dose-1 dependent antibacterial effects and 2 global gene expression changes in infant oral microbiota
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