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ProteomicsA mouse SWATH-MS reference spectral library enables deconvolution of species-specific proteomic alterations in human tumour xenografts
SWATH-MS enables accurate and reproducible label-free quantification of proteomes including in extensively studied model organisms such as the mouse. Here we present a comprehensive mouse reference spectral library (MouseRefSWATH) that allows quantification of up to 10,597 proteins (62.2% of mouse p...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2020-06-23 | PXD017209 | Pride
Swath-ms  breast cancer  dcis  mouse  human  xenograft model 
ProteomicsProteomic analysis of ECM-enriched fraction of breast xenograft and skin tissue from mice injected with 13C-glutamine
Elevated production of collagen-rich extracellular matrix (ECM) is a hallmark of cancer associated fibroblasts (CAFs) and a central driver of cancer aggressiveness. How to target ECM production to oppose cancer is yet unclear, since targeting CAFs has been shown to restrain but also promote cancer p...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-31 | PXD024746 | Pride
Collagen Xenograft tumour of mcf10dcis.com Breast cancer 
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