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TranscriptomicsTranscriptomics adaptation of porcine adipose- and bone marrow-derived stem cells during adipogenic and osteogenic differentiation
Adipose-derived and bone-marrow-derived mesenchymal stem cells were collected from 3 pigs and cultivated in vitro up to 3 passages. At passage 3 cells were cultured to 80% confluence and induced to differentiate in adipose and bone. Cell were harvested at 0 day of differentiation (dd) or pre-differe...
ORGANISM(S): Sus scrofa 
2012-03-01 | E-GEOD-25854 | biostudies-arrayexpress
TranscriptomicsWhole genome expression array profiling highlights differences in mucosal defense genes in Barrett's esophagus and esophageal adenocarcinoma.
Esophageal adenocarcinoma (EAC) has become a major concern in Western countries due to rapid rises in incidence coupled with very poor survival rates. One of the key risk factors for the development of this cancer is the presence of Barrett’s esophagus (BE), which is believed to form in response to ...
ORGANISM(S): Homo sapiens 
2011-08-16 | E-GEOD-28302 | biostudies-arrayexpress
GenomicsIntegrative fine-mapping of regulatory variants and mechanisms at coronary artery disease loci
Coronary artery disease (CAD) is the leading cause of mortality and morbidity driven by both genetic and environmental risk factors. Meta-analyses of genome-wide association studies (GWAS) have identified multiple single nucleotide polymorphisms (SNPs) associated with CAD and myocardial infarction (...
ORGANISM(S): Homo sapiens 
2016-07-06 | E-GEOD-72696 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of mesenchymal stem cells (MSC), osteoblasts and the U2OS (osteosarcoma) cell line
Transcriptional profiling of MSC, Osteoblasts and U2OS cells. The aim was to quantitate relative gene expression in MSC, osteoblasts and U2OS. MSC and osteoblasts were used as normal cells in this study because osteosarcoma most likely originates from MSC or osteoblasts. Cell culture and treatment: ...
ORGANISM(S): Homo sapiens 
2012-03-02 | E-GEOD-27900 | biostudies-arrayexpress
TranscriptomicsSuppression of Lung Adenocarcinoma Progression by Nkx2-1
Despite the high prevalence and poor outcome of patients with metastatic lung cancer, the mechanisms of tumour progression and metastasis remain largely uncharacterized. We modelled human lung adenocarcinoma, which frequently harbours activating point mutations in KRAS1 and inactivation of the p53-p...
ORGANISM(S): Mus musculus 
2011-01-27 | E-GEOD-26874 | biostudies-arrayexpress
TranscriptomicsPANC-1 cell differentiation
Multiple commercial microarrays for measuring genome-wide gene expression levels are currently available, including oligonucleotide and cDNA, single- and two-channel formats. This study reports on the results of gene expression measurements generated from identical RNA preparations that were obtaine...
ORGANISM(S): Homo sapiens 
2007-05-15 | E-GEOD-7785 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of adult male whole MutaMouse lung with its immortalized 100% confluent epithelial lung cell line counterpart UHN 15K Array
Biological comparison of gene expression profiles of a whole mouse lung from a transgenic mouse line with its immortalized cell line counterpart.
ORGANISM(S): Mus musculus 
2004-07-01 | E-MEXP-107 | biostudies-arrayexpress
UnknownComprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.
Not available
S-EPMC4530011 | biostudies-literature
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
UnknownBurden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life expectancy in 204 countries and territories, including 660 subnational locations, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.
Not available
S-EPMC12535840 | biostudies-literature
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