Human hepatocellular carcinoma cells were subcutaneously implanted into nude mice and treated with photodynamic nanoparticles (NP3) with laser, followed by tissue collection and proteomic analysis.
Insulin deficiency from β-cell dysfunction underpins both type 1 and type 2 diabetes. However, the regulatory pathways underlying β-cell function remain incompletely understood. Here, we identify that March5 and Trim28 as key modulators of β-cell function. March5 is downregulated and Trim28 upregula...