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UnknownOptimal timing for activation of sigma 1 receptor in the Pde6brd10/J (rd10) mouse model of retinitis pigmentosa.
Not available
S-EPMC7808329 | biostudies-literature
ProteomicsPrecision in Tear Fluid Biomarker Discovery: Quantitative Proteomic Profiling of Small-Volume, Individual Samples Using Capillary Tube Collection
Tear fluid, a complex biofluid that contains thousands of proteins and can be collected non-invasively, has emerged as a promising source of biomarkers for ocular and systemic health. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is currently the primary method for discovering novel biom...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD060101 | Pride
1. tear proteomics  2. tear biomarker  3. biomarker discovery  4. capillary collection  5. lc-ms/ms 
ProteomicsRapid Tear Proteomics via In-Capillary Digestion for Biomarker Discovery
Tear fluid is emerging as a valuable resource for biomarker discovery, but its low sample volume and dynamic composition pose significant challenges for analytical testing. Most tear proteomics studies have focused on samples collected with Schirmer strips, while capillary tube collection has receiv...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD056978 | Pride
1. tear proteomics  2. tear biomarker  3. biomarker discovery  4. point-of-care testing  5. poct  6. lc-ms/ms 
ModelsSluka2016 - Acetaminophen PBPK
Basic PBPK (Physiologically Based PharmacoKinetic) model of Acetaminophen. This is a basic model of Acetaminophen (APAP, Paracetamol) pharmacokinetics in humans. Many of the model parameters (compartment volumes, volumetric flow rates, etc.) are scaled allometrically based o...
2024-09-02 | BIOMD0000000619 | BioModels
UnknownEffect of long-term chronic hyperhomocysteinemia on retinal structure and function in the cystathionine-β-synthase mutant mouse.
Not available
S-EPMC9251730 | biostudies-literature
UnknownNeuronal α-Synuclein Disease Stage Progression over 5 Years.
Not available
S-EPMC12273616 | biostudies-literature
UnknownGenome sequence of the tobacco bacterial wilt pathogen Ralstonia solanacearum.
Not available
S-EPMC3194909 | biostudies-literature
UnknownIdentification of wounding and topping responsive small RNAs in tobacco (Nicotiana tabacum).
Not available
S-EPMC3306195 | biostudies-literature
UnknownLow expression of HIV genes in podocytes accelerates the progression of diabetic kidney disease in mice.
Not available
S-EPMC8006538 | biostudies-literature
UnknownQuadruplex-forming oligonucleotide targeted to the VEGF promoter inhibits growth of non-small cell lung cancer cells.
Not available
S-EPMC6347295 | biostudies-literature
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