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MetabolomicsLsr2, a novel cyclic di-GMP receptor, regulate the synthesis of keto-mycolic acid and control biofilm formation in mycobacteria

Cyclic di-GMP (c-di-GMP) is a well-known second messenger that plays a key role in many physiological processes in bacteria. The synthesis of lipids is essential for bacterial biofilm formation. However, whether c-di-GMP signaling modulates the synthesis of lipid and further regulates biofilm for...

2023-12-12 | MTBLS7053 | MetaboLights
UnknownHuman papillomavirus and rising oropharyngeal cancer incidence in the United States.
Not available
S-EPMC3221528 | biostudies-literature
UnknownGenomic Characteristics and E Protein Bioinformatics Analysis of JEV Isolates from South China from 2011 to 2018.
Not available
S-EPMC9412759 | biostudies-literature
ProteomicsA Quantitative Proteome Map of the Human Body
In this study, we quantified the relative protein levels from 12,627 genes across 32 normal human tissue types prepared by the GTEx project. Known and new tissue specific or enriched proteins were identified and compared to transcriptome data. Many ubiquitous transcripts are found to encode highly t...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-10-30 | MSV000086387 | MassIVE
ProteomicsIdentification the proteins interacted with ILF2 in human keratinocytes
By profiling lncRNA expression changes during human skin wound healing and screening lncRNA functions, we identified SNHG26 as a pivotal regulator in keratinocyte progenitors underpinning this phase transition. we performed RNA pull-down assay in human keratinocyte progenitors and found SNHG26 inter...
ORGANISM(S): Homo sapiens (Human) 
2024-08-28 | PXD055235 | Pride
Keratinocyte Ilf2 
ProteomicsIdentification the proteins interacted with SNHG26 in human keratinocytes
The cell transition from an inflammatory phase to a subsequent proliferative phase is crucial for wound healing, yet the driving mechanism remains unclear. By profiling lncRNA expression changes during human skin wound healing and screening lncRNA functions, we identified SNHG26 as a pivotal regulat...
ORGANISM(S): Homo sapiens (Human) 
2024-08-28 | PXD055231 | Pride
Snhg26 Keratinocyte 
ProteomicsGlycopeptidomics Analysis of a Cell Line Model Revealing Pathogenesis and Potential Marker Molecules for the Early Diagnosis of Gastric MALT Lymphoma
The relationship between the predominant glycoforms of host cells and the development of host disease was determined
ORGANISM(S): Homo Sapiens X Mus Musculus Hybrid Cell Line 
2021-06-25 | PXD026920 |
ProteomicsIn-vivo crosslinking based affinity purification-mass spectrometry for targeting intracellular protein-protein interactions
Comprehensive interactome analysis of targeted proteins is of great significance to understand how pro-teins work together for functional regulation. Until now, affinity purification strategy with mass spec-trometry (AP-MS) has been recognized as the most widely used technique for studying protein-p...
ORGANISM(S): Homo Sapiens 
2022-12-01 | PXD038473 |
ProteomicsCleavable Hydrophobic Derivatization Strategy for Enrichment and Identification of Phosphorylated Lysine Peptides
Herein, a cleavable hydrophobic derivatization (CHD) strategy was established for the enrichment and identification of pLys peptides. By CHD, 2,5-dioxopyrrolidin-1-yl-3-(decyldisulfanyl)propanoate (Dec-disulf-NHS) was synthesized to react with lysine dephosphorylated peptides, and then the derived p...
ORGANISM(S): Escherichia Coli 
2019-02-12 | PXD012682 |
ProteomicsSite-selective photo crosslink to methyllysine readers via single electron transfer between sulfonium and tryptophan
Reader proteins play significant roles in cell signaling from site-specific lysine methylation, but the progress of new reader investigations is rather slow. Photoreactive crosslinkers enable reader identifications, but it requires laborious chemical synthesis for optimization of the photoreactive g...
ORGANISM(S): Homo Sapiens 
2024-02-04 | PXD049149 |
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