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Objective: The aim of this study was to identify novel diagnostic biomarkers of diabetic vascular dementia (DVD) and unraveling the underlying mechanisms using mass spectrometry (MS). Methods: Label-Free LC-MS/MS proteomics analysis was applied to urine samples from four groups including 14 vascular...
ORGANISM(S): Homo sapiens (Human) 
2021-01-14 | PXD022189 | Pride
Tumor growth requires elevated ribosome biogenesis. Targeting ribosomes is an important strategy for cancer therapy. The ribosome inhibitor, homoharringtonine (HHT), is used for the clinical treatment of leukemia, yet it is ineffective for the treatment of solid tumors, the reasons for which remain ...
ORGANISM(S): Homo sapiens (Human) 
2023-09-26 | PXD045622 | Pride

Cyanobacterial harmful algal blooms (cHABs) dominated by Microcystis aeruginosa threaten the ecological integrity and beneficial uses of lakes globally. In addition to producing hepatotoxic microcystins (MC), M. aeruginosa exudates (MaE) contain various compounds with demonstrat...

2023-01-16 | MTBLS6603 | MetaboLights
Construct asthma mouse models using OVA and CFA, intervene with Warming Yang and Nourishing Kidney Approach and Xiao Qinglong Decoction respectively, and perform proteomic sequencing on the lung tissues of mice from control group-1, model group-1 and warming yang and tonifying kidney therapy group, ...
ORGANISM(S): Mus Musculus 小家鼠 
2024-11-15 | PXD058120 |
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