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MetabolomicsLow chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk
Dysregulated extravillous trophoblast invasion and proliferation are known to increase the risk of recurrent spontaneous abortion (RSA); however, the underlying mechanism remains unclear. Herein, in our retrospective observational case-control study we show that villous samples from RSA patients, co...
2021-10-06 | MTBLS2148 | MetaboLights
MetabolomicsComparative metabolomic analysis of exudates of microcystin-producing and microcystin-free Microcystis aeruginosa strains

Cyanobacterial harmful algal blooms (cHABs) dominated by Microcystis aeruginosa threaten the ecological integrity and beneficial uses of lakes globally. In addition to producing hepatotoxic microcystins (MC), M. aeruginosa exudates (MaE) contain various compounds with demonstrat...

2023-01-16 | MTBLS6603 | MetaboLights
UnknownComprehensive mutation screening for 10 genes in Chinese patients suffering very early onset inflammatory bowel disease.
Not available
S-EPMC4917618 | biostudies-literature
MetabolomicsBCAA insufficiency leads to premature ovarian insufficiency via ceramide-induced elevation of ROS (untargeted lipidomics)

Premature ovarian insufficiency (POI) is a disease featured by early menopause before 40 years of age, accompanied by an elevation of follicle-stimulating hormone. Though POI affects many aspects of women's health, its major causes remain unknown. Many clinical studies have shown that POI patient...

2024-09-26 | MTBLS6249 | MetaboLights
UnknownTargeting miR-30d reverses pathological cardiac hypertrophy.
Not available
S-EPMC9240797 | biostudies-literature
TranscriptomicsTesticular germ cell tumor susceptibility genes from the consomic 129.MOLF-Chr19 mouse strain
Chromosome substitution strains (CSS or consomic strains) are useful for mapping phenotypes to chromosomes. However, huge efforts are needed to identify the gene(s) responsible for the phenotype in the complex context of the chromosome. Here, we report the identification of candidate disease genes...
ORGANISM(S): Mus musculus 
2009-01-13 | E-GEOD-14354 | biostudies-arrayexpress
MetabolomicsMultiple biochemical indices and metabolomics of Clonorchis sinensis provide a novel interpretation of biomarkers

BACKGROUND: Clonorchiasis, an infectious disease caused by the liver fluke Clonorchis sinensis, may lead to the development of liver and gallbladder diseases, and even cholangiocarcinoma (CCA). However, the pathogenesis, host-pathogen interaction, and diagnostic markers ...

2022-06-24 | MTBLS3306 | MetaboLights
UnknownCopper-catalyzed borofunctionalization of styrenes with B2pin2 and CO.
Not available
S-EPMC8549821 | biostudies-literature
UnknownRuthenium pincer complex-catalyzed heterocycle compatible alkoxycarbonylation of alkyl iodides: substrate keeps the catalyst active.
Not available
S-EPMC8864804 | biostudies-literature
UnknownCopper-catalyzed enantioselective carbonylation toward α-chiral secondary amides.
Not available
S-EPMC8494041 | biostudies-literature
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