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MetabolomicsMetabolomic approaches to dissect dysregulated metabolism in the progression of pre-diabetes to T2DM

Most of pre-diabetes were eventually progress to diabetes, thereby profiling of prediabetic metabolic disorders may be an effective targeted preventive measure. We aimed to elucidate internal motivation of the progression of pre-diabetes to type 2 diabetes mellitus (T2DM) from a metabolic perspec...

2024-04-29 | MTBLS8644 | MetaboLights
MetabolomicsMetabolome-based prediction of yield heterosis contributes to the breeding of elite rice
The improvement of breeding efficiencies for heterotic and climate-resilient crops can mitigate the food shortage crisis from overpopulation and climate change. Thus far, diverse molecular markers have been utilized for guiding field phenotypic selections, while the accurate predictions of complex h...
2019-12-10 | MTBLS742 | MetaboLights
TranscriptomicsGene expression signatures for mESC treated by RNAi strategy on down regulation of gene Mtf2
To further explore the function of Mtf2, the homolog of Drosophila Polycomb group gene PCL, we have employed the mouse whole genome microarray expression profiling as a discovery platform to identify genes mediated by Mtf2. Oligos of 2 different RNAi target sites on gene Mtf2 were cloned into RNAi V...
ORGANISM(S): Mus musculus 
2010-02-20 | E-GEOD-18319 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human, mouse, Bos taurus embryo
The process of early development of mammals is subtly and accurately controlled by the regulation networks of embryo cells. Time course expression data measured at different stages during early embryo development process can give us valuable information by revealing the dynamic expression patterns o...
ORGANISM(S): Bos taurus 
2009-10-02 | E-GEOD-18290 | biostudies-arrayexpress
ProteomicsHapMap_LCL_TMT_quant_2
Variation and genetic control of protein abundance in humans, 2
ORGANISM(S): Homo Sapiens (human) 
2013-12-31 | PAe005077 | PeptideAtlas
ProteomicsHapMap_LCL_TMT_quant_1
Variation and genetic control of protein abundance in humans, 1
ORGANISM(S): Homo Sapiens (human) 
2013-12-31 | PAe004978 | PeptideAtlas
ProteomicsAnalysis of protein expression changes in patients with prediabetes using high-throughput proteomics
Objective: This study aimed to explore the mechanisms of early-onset T2DM by analyzing proteomic changes at different stages of glucose metabolism. Methods: A total of 40 individuals undergoing routine physical health examinations between December 2016 and April 2017 were enrolled. Subjects were di...
ORGANISM(S): Homo Sapiens 
2022-10-19 | PXD035367 |
TranscriptomicsPostia placenta MAD-698 gene expression in different media
Transscript profiles of Postia placenta grown on different substrates were analyszed. Array design was based on the DoE's Joint Genome Institute's gene models for P. placenta version 1. The research goal is to identtify genes essential for cellulose depolymerization. Keywords: Culture condition com...
ORGANISM(S): Postia placenta 
2010-05-14 | E-GEOD-12540 | biostudies-arrayexpress
ProteomicsMouse multi-organ age-associated protein changes across life stages
Ageing is a key risk factor for disease and mortality in humans and other animals, with most insights derived from genomic, epigenomic, and transcriptomic studies. However, large-scale datasets on age-related changes at the protein level remain scarce. To fill this gap, we performed a comprehensive ...
ORGANISM(S): Mus Musculus (mouse) 
2025-06-17 | PXD058684 | JPOST Repository
UnknownPrimary Mechanism Study of Panax notoginseng Flower (Herb) on Myocardial Infarction in Rats.
Not available
S-EPMC6525894 | biostudies-literature
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