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TranscriptomicsProteomic and transcriptomic responses to thiamethoxam in the Sweetpotato whitefly, Bemisia tabaci (Hemiptera: Aleyrodidae)
We investigated the transcriptional response to thiamethoxam in the Bemisia tabaci using Illumina sequencing technology. A total of 1,338 genes were differently expressed in the thiamethoxam-resistant whiteflies. All the B biotype whiteflies were maintained on cabbage. The susceptible strain (TH-S)...
ORGANISM(S): Bemisia tabaci 
2013-07-15 | E-GEOD-42102 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of Bemisia tabaci reveals stage-specific gene expression signatures for thiamethoxam resistance
To investigated the stage-specific gene expression response to thiamethoxam in the Bemisia tabaci, we have designed the Agilent eArray platform to identify stage-regulated gene expression towards thiamethoxam exposure. All the B biotype Bemisia tabaci were maintained on cabbage. Thiamethoxam suscept...
ORGANISM(S): Bemisia tabaci 
2013-11-01 | E-GEOD-42337 | biostudies-arrayexpress
GenomicsThe landscape of accessible chromatin in mammalian pre-implantation embryos (ChIP -Seq)
In mammals, extensive chromatin reorganization is essential for reprogramming terminally committed gametes to a totipotent state during preimplantation development. However, the global chromatin landscape and its dynamics in this period remain unexplored. Here we report a genome-wide map of accessib...
ORGANISM(S): Mus musculus 
2016-06-15 | E-GEOD-79935 | biostudies-arrayexpress
TranscriptomicsRepeat elements study in pluripotent stem cells [RNA-seq]
We surveyed RNA-Seq data to identify those TEs that are transcriptionally active uniquely in human pluripotent cells. We identified one endogenous retrovirus (HERV-H) family, uniquely found in primates as being unusually abundant in the transcriptome. Poly(A)+ RNA extraction and further sequencing l...
ORGANISM(S): Homo sapiens 
2014-10-09 | E-GEOD-44646 | biostudies-arrayexpress
TranscriptomicsIdentification and characterization of FGF2-dependent mRNA:microRNA networks during lens fiber cell differentiation
Background: FGF signaling controls numerous processes during cell lineage specification, organogenesis and terminal differentiation. In lens, FGF signaling was implicated as the key pathway that controls lens fiber cell differentiation, but little is known about its full range and spectrum of regula...
ORGANISM(S): Rattus norvegicus 
2013-09-06 | E-GEOD-50604 | biostudies-arrayexpress
GenomicsThe landscape of accessible chromatin in mammalian pre-implantation embryos (ATAC-Seq)
In mammals, extensive chromatin reorganization is essential for reprogramming terminally committed gametes to a totipotent state during preimplantation development. However, the global chromatin landscape and its dynamics in this period remain unexplored. Here we report a genome-wide map of accessib...
ORGANISM(S): Mus musculus 
2016-06-15 | E-GEOD-66581 | biostudies-arrayexpress
TranscriptomicsThe landscape of accessible chromatin in mammalian pre-implantation embryos (RNA-Seq)
In mammals, extensive chromatin reorganization is essential for reprogramming terminally committed gametes to a totipotent state during preimplantation development. However, the global chromatin landscape and its dynamics in this period remain unexplored. Here we report a genome-wide map of accessib...
ORGANISM(S): Mus musculus 
2016-06-15 | E-GEOD-66582 | biostudies-arrayexpress
Transcriptomicsrepeat elements study in pluripotent stem cells [expression array]
We surveyed RNA-Seq data to identify those TEs that are transcriptionally active uniquely in human pluripotent cells. We identified one endogenous retrovirus (HERV-H) family, uniquely found in primates as being unusually abundant in the transcriptome. The microarray data provided is to support our h...
ORGANISM(S): Homo sapiens 
2014-10-09 | E-GEOD-54725 | biostudies-arrayexpress
TranscriptomicsStudy of gene expression of mouse cMET experiments
We analyzed the molecular changes in a mouse c-MET over-expression model of hepatocellular carcinoma (HCC). FVB mice overexpressing human c-MET carried one copy of the LAP-tTa transgene (the liver-specific LAP promoter driving the Tet-VP16 transactivator) and one copy of the TRE-c-MET transgene (Tet...
ORGANISM(S): Mus musculus 
2011-08-14 | E-GEOD-25142 | biostudies-arrayexpress
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