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UnknownCombining Network Pharmacology and Experimental Verification to Investigate the Protective Effect of Melatonin on Fluoride-Induced Brain Injury.
Not available
S-EPMC12944959 | biostudies-literature
UnknownPhase IIb trial of in vivo electroporation mediated dual-plasmid hepatitis B virus DNA vaccine in chronic hepatitis B patients under lamivudine therapy.
Not available
S-EPMC5236510 | biostudies-literature
Proteomicsp38 mediated ACSL4 phosphorylation drives stress-induced esophageal squamous cell carcinoma growth through Src myristoylation
Through IP/MS, we discovered that ACSL4 could interact with p38
ORGANISM(S): Homo sapiens (Human) 
2025-03-08 | PXD053908 | Pride
Human escc 
ProteomicsProteomic Analysis of Huh7, HIEC6, and NCI-H295R cells using High-affinity anti-Golm1 mAb by IP-MS.
we conducted IP-MS strategy to screen its interacting proteins. High-affinity anti-Golm1 mAb and IgG were used in multiple cell lines including Huh7, HIEC6, and NCI-H295R cells. Proteins with more than two peptide segments enriched or exclusively within the Golm1 group were identified as putative in...
ORGANISM(S): Homo sapiens (Human) Homo sapiens 
2026-03-23 | PXD061115 | Pride
Golm1 ip-ms 
UnknownAnti-angiogenic therapy or immunotherapy? A real-world study of patients with advanced non-small cell lung cancer with EGFR/HER2 exon 20 insertion mutations.
Not available
S-EPMC10985835 | biostudies-literature
Unknownα1,6-Fucosyltransferase (FUT8) regulates the cancer-promoting capacity of cancer-associated fibroblasts (CAFs) by modifying EGFR core fucosylation (CF) in non-small cell lung cancer (NSCLC).
Not available
S-EPMC7136908 | biostudies-literature
ProteomicsCross-sectional study of proteomic differences between moderate and severe psoriasis
Background: Although there is an ongoing understanding of psoriasis vulgaris (PV) pathogenesis, little is known about the proteomic diversity of psoriatic lesions between moderate and severe psoriasis. Objective: To evaluate the proteomic differences between moderate and severe psoriasis and determi...
ORGANISM(S): Homo Sapiens 
2024-06-06 | PXD052886 |
MetabolomicsSensing Ceramides by CYSLTR2 and P2RY6 to Aggravate Atherosclerosis

Recent evidence shows elevated circulating long-chain ceramide levels predicts atherosclerotic cardiovascular disease (ASCVD) independently of cholesterol. Although targeting ceramides signaling may provide therapeutic benefits beyond the treatment of hypercholesterolemia, the underlying mechanis...

2025-04-15 | MTBLS11925 | MetaboLights
UnknownPlio-Pleistocene evolution of Bohai Basin (East Asia): demise of Bohai Paleolake and transition to marine environment.
Not available
S-EPMC4935998 | biostudies-literature
ProteomicsIL-17A and TNF-α inhibitors induce multiple molecules andsignal pathway change in psoriasis
Adalimumab and secukinumab are commonly used for moderate-severe psoriasis vulgaris (PV), but distinct individual response and impaired effectiveness happen occasionally. Little is known about it. Here, we report a proteomic analysis of psoriatic lesions from patients treated with these drugs using ...
ORGANISM(S): Homo Sapiens 
2022-10-20 | PXD037579 |
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