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ProteomicsProteomic analysis of Dpy19l2-deficient human globozoospermia reveals multiple molecular defects
Globozoospermia is a severe teratozoospermia characterized by round-headed spermatozoa without acrosomes, resulting in male infertility. The clinical treatment of globozoospermia involves primarily intracytoplasmic sperm injection because of the low fertilization rate. The deletion of Dpy19l2 is kno...
ORGANISM(S): Homo sapiens (Human) 
2019-08-15 | PXD012302 | Pride
Proteomics Dpy19l2 Human Globozoospermia Round-headed 
UnknownAltruistic behaviors relieve physical pain.
Not available
S-EPMC6969495 | biostudies-literature
TranscriptomicsSilencing or amplification of endocannabinoid signaling in blastocysts via CB1 compromises trophoblast cell migration
Endocannabinoid signaling plays a key role in multiple events in female reproduction. In this investigation, we discovered an interesting phenomenon that mice with either elevated or silenced endocannabinoid signaling show similar defects in multiple pregnancy events, including preimplantation embry...
ORGANISM(S): Mus musculus 
2012-07-25 | E-GEOD-36399 | biostudies-arrayexpress
Genomicsena-DATASET-BGI-18-06-2015-05:57:10:511-19 - samples
We sequenced 205 patients who were suffering NSCLC with Exome sequencing method.
EGAD00001001398 | EGA
Genomicsena-DATASET-BGI-18-06-2015-04:55:13:301-17 - samples
We sequenced 292 patients who were suffering NSCLC with Whole genome sequencing or Exome sequencing method.
EGAD00001001397 | EGA
GenomicsFrequent alterations in cytoskeleton remodeling genes in primary and metastatic Chinese lung adenocarcinomas
The landscape of genetic alterations in lung adenocarcinoma derived from Asian patients is largely uncharacterized. Here we present an integrated genomic and transcriptomic analysis of 335 primary lung adenocarcinomas and 35 corresponding lymph node metastases from Chinese patients. Altogether 13 si...
EGAS00001000982 | EGA
GenomicsBGI Data Access Committee
Data Access Committee EGAC00001000177
EGAC00001000177 | EGA
ProteomicsUnveiling Biomarkers of Telitacicept’s Efficacy in SLE Treatment Through Proteomics
Our study is highly relevant to the fields of Medical Bioinformatics and Personalised Medicine, as it employs high-throughput omics technologies and bioinformatics analyses to uncover personalized biomarkers predictive of treatment response, thereby paving the way for tailored therapeutic strategi...
ORGANISM(S): Homo Sapiens 
2026-02-02 | PXD073923 |
ProteomicsPorphyromonas gingivalis infection and atherosclerosis
To explore the effect of Porphyromonas gingivalis on lipid-laden macrophages, the project was conduct. Overall design: 8 samples, 4 replicates in 2 groups, with ox-LDL-treated RAW264.7 macrophages stimulated with or without Porphyromonas gingivalis.
ORGANISM(S): Mus Musculus 
2024-01-09 | PXD048371 |
ProteomicsSerum integrative omics reveals the landscape of human diabetic kidney disease
Diabetic kidney disease (DKD) is the most common microvascular complication of type 2 diabetes mellitus (2-DM). Currently, urine and kidney biopsy specimens are the major clinical resources for DKD diagnosis. The diagnostic values of blood in monitoring the onset and progression of DKD have not been...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-05-22 | MSV000087487 | MassIVE
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