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Bovine tuberculosis (bTB), primarily caused by Mycobacterium bovis (M. bovis), is a globally zoonotic disease with significant economic impacts. Plasma exosomes have been extensively used for investigating disease processes and exploring biomarkers. While mass spectrometry (MS)-based proteomic analy...
ORGANISM(S): Bos Taurus 
Liver fibrosis is the initial stage of most liver diseases, and it is also a pathological process involving the liver in the late stages of many metabolic diseases. Therefore, it is important to systematically understand the pathological mechanism of liver fibrosis and seek therapeutic approaches fo...
ORGANISM(S): Mus Musculus 
2025-01-16 | PXD059906 |
HOIP truncations proteins GST-PUB, GST-NZF, GST-UBA and GST-RBR-LDD were purified, GST was used as a negative control. The tissue lysates from the C57BL/6 mice were incubated with glutathione-S-transferase (GST) beads which bound to the GST-HOIP truncation proteins beforehand. The pull-down componen...
ORGANISM(S): Mus Musculus 
2024-02-28 | PXD043322 |
When cells encounter proteome stresses, caspase-2 accumulates in a ubiquitin-rich condensate, which functions as a deubiquitinase to cleave the overloaded ubiquitinated proteins.
ORGANISM(S): Homo Sapiens 
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