Sort   by:  
 Page size 
TranscriptomicsAdult Human Chondrocyte Response to IL-1B
IL-1B is an important cytokine that is often found to be up-regulated during osteoarthritic and rheumatoid joint diseases. It is viewed as a catabolic factor, inducing enzymes that allow for the degradation of the cartilage extracellular matrix and also has essential roles as an autocrine and parac...
ORGANISM(S): Homo sapiens 
2008-05-14 | E-GEOD-11427 | biostudies-arrayexpress
GenomicsMethylation dynamics of mouse neuron by MeDIP-seq and MRE-seq
Study DNA methylation of mouse neuron using MeDIP-seq and MRE-seq DNA methylation of mouse neuron using MeDIP-seq and MRE-seq
ORGANISM(S): Mus musculus 
2015-02-20 | E-GEOD-53694 | biostudies-arrayexpress
TranscriptomicsMapping of variable DNA methylation across multiple cell types defines a dynamic regulatory landscape of the human genome
DNA methylation is an important epigenetic modification involved in many biological processes and diseases. Many studies have mapped DNA methylation changes associated with embryogenesis, cell differentiation and cancer at a genome-wide scale. Our understanding of genome-wide DNA methylation changes...
ORGANISM(S): Homo sapiens 
2016-04-06 | E-GEOD-69894 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of histone modification, protein-DNA binding, cytosine methylation and transcriptome data in mouse and human ES cells and pig iPS cells
Genome-wide analysis of histone modification (H2AZ, H3K27ac, H3K27me3, H3K36me3, H3K4me1, H3K4me2, H3K4me3 and H3K9me3), protein-DNA binding (TAF1, P300, Pou5f1 and Nanog), cytosine methylation and transcriptome data in mouse and human ES cells and pig iPS cells We generated histone modification da...
ORGANISM(S): Homo sapiens 
2012-02-28 | E-GEOD-36114 | biostudies-arrayexpress
GenomicsWidespread contribution of transposable elements to the innovation of gene regulatory networks [human ENCODE]
Transposable elements (TE) have been shown to contrain functional transcription factor (TF) binding sites for long, but the extent to which TEs contribute TF binding sites is not well know. Here, we comprehensively mapped binding sites for 26 pairs of orthologous TFs, in two pairs of human and mouse...
ORGANISM(S): Homo sapiens 
2014-05-09 | E-GEOD-56774 | biostudies-arrayexpress
GenomicsWidespread contribution of transposable elements to the innovation of gene regulatory networks [mouse ENCODE]
Transposable elements (TE) have been shown to contrain functional transcription factor (TF) binding sites for long, but the extent to which TEs contribute TF binding sites is not well know. Here, we comprehensively mapped binding sites for 26 pairs of orthologous TFs, in two pairs of human and mouse...
ORGANISM(S): Mus musculus 
2014-05-09 | E-GEOD-57230 | biostudies-arrayexpress
GenomicsGenome-wide analysis of K3K27ac, H2AZ and methylation data in mouse embryonic stem cells
We generated two types 5-methylcytosine (5-mC) data in E14 mouse embryonic stem cells, using methylated DNA immunoprecipitation followed by sequencing (MeDIP-seq) and DNA digestion by methyl-sensitive restriction enzymes followed by sequencing (MRE-seq). Examination of 2 histone modifications and me...
ORGANISM(S): Mus musculus 
2014-01-09 | E-GEOD-34953 | biostudies-arrayexpress
ProteomicsRepression of EGLN1 activity by SET7-catalyzed methylation
Repression of EGLN1 activity by SET7-catalyzed methylation
ORGANISM(S): Homo Sapiens 
2022-03-08 | PXD032126 |
ProteomicsArginine GlcNAcylation of Rab small GTPases by the pathogen Salmonella Typhimurium
We determined the GlcNAcyaltion of Rab1 by a Salmonella T3SS effector SseK3. IP experiments were performed from HEK293 cells and MS files were acquired on Q Exactive mass spectrometer. We analysed the differences of protein abundance, comparing the normalized intensity on distinct proteins from diff...
ORGANISM(S): Homo Sapiens Escherichia Coli Mus Musculus 
2020-06-05 | PXD019062 |
ProteomicsIdentification of IRF3 hydroxylation site
Identification of IRF3 hydroxylation site in cells
ORGANISM(S): Homo Sapiens 
2024-03-12 | PXD050566 |
Sort   by:  
 Page size