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Implant-associated infection and inadequate osseointegration remain the primary challenges for orthopedic implants. These risks are heightened in cases of severe trauma or infection at the implantation site and in patients with severe osteoporosis or poorly controlled diabetes, where osseointegratio...
ORGANISM(S): Staphylococcus aureus subsp. aureus NCTC 8325 
2026-09-14 | PXD072593 | Pride
Long non-coding RNA HOX transcript antisense RNA (HOTAIR) is involved in human tumorigenesis and dysregulated in hepatocellular carcinoma (HCC). However, the molecular mechanisms underlying HOTAIR functions in HCC are not well understood. Here, an integrated RNA sequencing transcriptomic and quantit...
ORGANISM(S): Homo sapiens (Human) 
2017-11-24 | PXD006554 | Pride
Carcinoma cells can acquire key malignant traits by reprogramming their differentiation state via an epithelial-to-mesenchymal transition (EMT). Cancer cells that undergo EMT become invasive and resist a wide range of therapies including most chemotherapy drugs and radiation. Such cells are also ab...
ORGANISM(S): Homo sapiens 
We employed ChIRP in combination with proteomic strategy to systematically discover HOTAIR-interacting proteins. Three independent biological replicates of ChIRP-MS experiment were performed, alongside negative controls.
ORGANISM(S): Homo sapiens (Human) 
2021-07-09 | PXD015546 | Pride
Co-IP assays and Proteomics were performed to identify potential E3 ligases interacted with both cyclin D1 T286A and cyclin D1 T288A.
ORGANISM(S): Homo Sapiens 
2024-05-17 | PXD052332 |
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