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Proteomicsp-FADD-CD8+T cell axis determines hepatocellular carcinoma response to immune checkpoint inhibitors
The heterogenicity of hepatocellular carcinoma (HCC) remains a key obstacle in turning the majority of ‘immune-cold’ tumors ‘hot’ for effective immune checkpoint inhibitors (ICIs). Through analyzing the naturally-existed ‘hot’ HCC variants, we identified fas-associated death domain (FADD) as a key m...
ORGANISM(S): Homo sapiens (Human) 
2025-07-07 | PXD057519 | Pride
Hcc Fadd Hepg2 
UnknownT cell–derived inducible nitric oxide synthase switches off Th17 cell differentiation.
Not available
S-EPMC3698516 | biostudies-literature
UnknownSpecies Quantification in Complex Herbal Formulas-Vector Control Quantitative Analysis as a New Method.
Not available
S-EPMC7725679 | biostudies-literature
UnknownFibrillarin Contributes to the Oncogenic Characteristics of Colorectal Cancer Cells and Reduces Sensitivity to 5-Fluorouracil.
Not available
S-EPMC12730408 | biostudies-literature
TranscriptomicsIdentification of miRNAs and Their Target Genes in Peach (Prunus persica L.) Using High-Throughput Sequencing and Degradome Analysis
MicroRNAs play critical roles in various biological and metabolic processes. The function of miRNAs has been widely studied in model plants such as Arabidopsis and rice. However, the number of identified miRNAs and related miRNA targets in peach (Prunus persica) is limited. To understand further the...
ORGANISM(S): Prunus persica 
2014-01-01 | E-GEOD-49579 | biostudies-arrayexpress
UnknownDevelopment and clinical deployment of a smartphone-based visual field deep learning system for glaucoma detection.
Not available
S-EPMC7508974 | biostudies-literature
ProteomicsCSTB increases autophagic flux by sustaining the proteolytic activity of Cathepsin B and fuels glycolysis in pancreatic cancer
Cathepsins interact with CSTB were analysed by LC/MS
ORGANISM(S): Homo Sapiens 
2022-11-05 | PXD037970 |
ProteomicsTargeting vulnerable microcircuit in the ventral hippocampus of male transgenic mice to rescue Alzheimer-like social memory loss
Background:Episodic memory loss is a prominent clinical manifestation of Alzheimer's disease(AD), which is closely related to tau pathology and hippocampal impairment. Given the heterogeneity of brain neurons, the precise role of different brain neurons in terms of their sensitivity to tau accumulat...
ORGANISM(S): Mus Musculus 
2023-07-19 | PXD043883 |
UnknownConnecting single-cell transcriptomes to projectomes in mouse visual cortex.
Not available
S-EPMC10760188 | biostudies-literature
UnknownClimate Effects on Belowground Tea Litter Decomposition Depend on Ecosystem and Organic Matter Types in Global Wetlands.
Not available
S-EPMC11636250 | biostudies-literature
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