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ProteomicsReverse Genetics-Rescued Virulent Feline Calicivirus FCV-BJ616 Recapitulates Systemic Disease and Cytokine Storm in Cats
Feline calicivirus (FCV) is a key pathogen causing upper respiratory diseases and oral ulcers in cats, with significant genetic variability. This study aimed to isolate the FCV-BJ616 strain, investigate its pathogenic mechanisms, and provide insights for developing antibody therapies and broad-spect...
ORGANISM(S): Felis chaus 
2026-02-02 | PXD070016 | Pride
Proteomics. Feline calicivirus Reverse genetics of viruses 
ProteomicsTo identify serum ACSL4, ACSL5 and S100A2 as novel biomarkers for the diagnosis and prognosis assessment of feline calicivirus (FCV) infection
This study focuses on lung injury and related protein changes caused by feline calicivirus (FCV) infection, aiming to provide a theoretical basis for the diagnosis, treatment, and prognosis evaluation of FCV infection. First, we investigated the geographical distribution of 69 FCV strains from diffe...
ORGANISM(S): Felis chaus 
2025-12-11 | PXD070490 | Pride
Serum proteomics Biomarkers 
MetabolomicsStudy on the Hepatoprotection of Schisandra chinensis Caulis Ploysaccharides in nonalcoholic fatty liver disease in rats based on metabolomics

The aim of this study was to investigate the hepatoprotection of Schisandra chinensis Caulis polysaccharides (SCP) in the nonalcoholic fatty liver disease (NAFLD) induced by high-fat diet (HFD) in rats. A total of 30 Wistar rats were randomly divided into control group (CON), model group...

2021-08-24 | MTBLS3194 | MetaboLights
TranscriptomicsExpression data from early diphyodont morphogenesis in minature pig
The miniature pig is diphyodont, making it a valuable alternative model for understanding human tooth development and replacement. However, little is known about gene expression and function during swine odontogenesis. The goal of this study is to undertake the survey of differential gene expressio...
ORGANISM(S): Sus scrofa 
2014-12-23 | E-GEOD-53182 | biostudies-arrayexpress
TranscriptomicsMicroarray for LPS-stimulated B cells compared to unstimulated B cells
Both multiple myeloma (MM) and systemic lupus erythematosus (SLE) are characterized with abnormal production of plasma cells. To explore the novel therapeutic target to plasma cells, we determined the gene expression profile in plasma cells by affymetrix microarrays. LPS could effectively in vitro i...
ORGANISM(S): Mus musculus 
2019-08-01 | E-MTAB-7109 | biostudies-arrayexpress
TranscriptomicsMicroarray for B cells of TACI-IgG-treated MRL/lpr mice compared to control mice
Both multiple myeloma (MM) and systemic lupus erythematosus (SLE) are characterized with abnormal production of plasma cells. In both diseases, the process of B cells differentiate into plasmablast/plasma cell is disordered. Despite the continuous research on the development of prognostic factors an...
ORGANISM(S): Mus musculus 
2019-07-30 | E-MTAB-7106 | biostudies-arrayexpress
TranscriptomicsMicroarray for activated B cells compared to naive B cells
B cells encounter antigen to activate and then differentiate into plasma cells. Both multiple myeloma (MM) and some autoimmune diseases such as multiple sclerosis (MS) and systemic lupus erythematosus (SLE) are characterized with abnormal production of plasma cells. In both diseases, the process of ...
ORGANISM(S): Mus musculus 
2019-08-01 | E-MTAB-7110 | biostudies-arrayexpress
TranscriptomicsRNA-seq of mouse myeloma cell line SP 2/0 overexpressed with BC094916 against vector control
We found that a novel gene BC094916 mRNA significantly decreased in plasma cells. Because of plasmablast-like, mus musculus myeloma SP 2/0 cell line was selected to test the effect of BC094916 overexpression on plasmablast/plasma cells. BC094916 cDNA (General Biosystems, Anhui, China) was cloned int...
ORGANISM(S): Mus musculus 
2019-08-07 | E-MTAB-7105 | biostudies-arrayexpress
TranscriptomicsRNA-seq of mouse myeloma cell line SP 2/0 cells compared to naive B cells
Both multiple myeloma (MM) and systemic lupus erythematosus (SLE) are characterized with abnormal production of plasma cells. In both diseases, the process of B cells differentiate into plasmablast/plasma cell is disordered. Despite the continuous research on the development of prognostic factors an...
ORGANISM(S): Mus musculus 
2019-07-31 | E-MTAB-7112 | biostudies-arrayexpress
ProteomicsEffects of corosolic acid on protein expression of in Bel-7402 and Bel-7404 cells
We treated Bel-7402 and Bel-7404 cells with corosolic acid, and then used TMT to analyze protein expression in both cell lines after treatment with corosolic acid
ORGANISM(S): Homo Sapiens 
2022-04-27 | PXD033462 |
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