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UnknownSingle amino acid mutation of SR-BI decreases infectivity of hepatitis C virus derived from cell culture in a cell culture model.
Not available
S-EPMC5537182 | biostudies-literature
ProteomicsDiptoindonesin G is a middle domain HSP90 modulator for cancer treatment
HSP90 inhibitors can target many oncoproteins simultaneously, but none have made it through clinical trials due to dose-limiting toxicity and induction of heat shock response, leading to clinical resistance. We identified diptoindonesin G (dip G) as an HSP90 modulator that can promote degradation of...
ORGANISM(S): Homo sapiens (Human) 
2022-11-16 | PXD035398 | Pride
Esr1  hsp90  heat shock  lbd mutations  diptoindonesin g  hsp90 inhibitor  y537s  hsp90 middle domain  er alpha 
UnknownStatin initiation and risk of incident kidney disease in patients with diabetes.
Not available
S-EPMC10228577 | biostudies-literature
UnknownCrystal structure of a constitutive active mutant of adenosine A2A receptor.
Not available
S-EPMC9067115 | biostudies-literature
MetabolomicsTranscriptomic and metabolomic analyses reveal the differential accumulation of phenylpropanoids and terpenoids in hemp autotetraploid and its diploid progenitor

Background

Cannabis sativa, a dioecious plant that has been cultivated worldwide for thousands of years, is known for its secondary metabolites, especially cannabinoids, which possess several medicinal effects. In this study, we investigated the autopolyploidization effects on the biosynthes...
2023-09-21 | MTBLS6032 | MetaboLights
UnknownHLA-G 3'UTR polymorphism diplotypes and soluble HLA-G plasma levels impact cervical cancer susceptibility and prognosis.
Not available
S-EPMC9810980 | biostudies-literature
ProteomicsCN-CHPP 2015 Testis Project - Tissue-Based Proteogenomics Reveals that Human Testis Endows Plentiful Missing Proteins
The testis tissue-based trans-omics was a feasible approach to find more missing proteins (MPs) because it was reported higher gene expression found in testis tissues. Three testis tissues and two protein separation strategies were selected to quantitatively evaluate gene expression abundance at the...
ORGANISM(S): Homo sapiens (Human) 
2015-11-03 | PXD002179 | Pride
Transcriptome Testis Chromosome-centric human proteome project Proteome Missing proteins 
UnknownThe formation and stabilization of a novel G-quadruplex in the 5'-flanking region of the relaxin gene.
Not available
S-EPMC3283602 | biostudies-literature
UnknownStrong ferromagnetism of g-C3N4 achieved by atomic manipulation.
Not available
S-EPMC10119309 | biostudies-literature
MetabolomicsBased on the Metabolomic Approach the Energy Metabolism Responses of Oriental River Prawn Macrobrachium nipponense Hepatopancreas to Acute Hypoxia and Reoxygenation
Hypoxia represents a major physiological challenge for prawns and is a problem in aquaculture. Therefore, an understanding of the metabolic response mechanism of economically important prawn species to hypoxia and re-oxygenation is essential. However, little is known about the intrinsic mechanisms b...
2021-05-17 | MTBLS584 | MetaboLights
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