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TranscriptomicsGene Expression Profile for knocking down Tet1 in pre-iPSCs culturing in Vc medium.
Tet1 is a hydroxylase known for its role in the conversion of 5-methylcytosines (5mC) to 5-hydroxymethylcytosines (5hmC) involved in the possible active demethylation process and gene expression regulation. As somatic cell reprogramming involves the re-activation of pluripotency genes and the silenc...
ORGANISM(S): Mus musculus 
2013-10-27 | E-GEOD-48206 | biostudies-arrayexpress
GenomicsTet and TDG Mediate DNA Demethylation Essential for MET in Somatic Cell Reprogramming
Tet-mediated DNA oxidation is a new type of epigenetic modification in mammals and its role in the regulation of cell fate transition remains poorly understood. Here, we derive mouse embryonic fibroblasts (MEFs) deleted in all three Tet genes and examine their capability to be reprogrammed into iPS ...
ORGANISM(S): Mus musculus 
2014-02-19 | E-GEOD-52741 | biostudies-arrayexpress
GenomicsGenome-Wide Association Studies in Upper Gastrointestinal Cancers (Asian)

This project aims to conduct genome-wide association studies (GWAS) in two anatomically different upper gastrointestinal (UGI) cancer sites in two populations with distinctly different disease rates and genetic profiles. One population has very high rates for both esophageal squamous cel...

phs000361.v1.p1 | EGA
UnknownShort-term Outcomes of Laparoscopy-Assisted vs Open Surgery for Patients With Low Rectal Cancer: The LASRE Randomized Clinical Trial.
Not available
S-EPMC9478880 | biostudies-literature
UnknownEfficacy of antihypertensive treatment for target organ protection in patients with masked hypertension (ANTI-MASK): a multicentre, double-blind, placebo-controlled trial.
Not available
S-EPMC11293515 | biostudies-literature
UnknownContinual Decline in Azole Susceptibility Rates in Candida tropicalis Over a 9-Year Period in China.
Not available
S-EPMC8299486 | biostudies-literature
UnknownEasyMetagenome: A user-friendly and flexible pipeline for shotgun metagenomic analysis in microbiome research.
Not available
S-EPMC11865343 | biostudies-literature
UnknownWhole-genome sequence-based analysis of thyroid function.
Not available
S-EPMC4366514 | biostudies-literature
UnknownRare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity.
Not available
S-EPMC5491520 | biostudies-literature
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
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