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ProteomicsCircadian proteome atlas of wild-type and Per1-/-/Per2-/- mice models across eight organs
a circadian proteome atlas of eight organs, namely suprachiasmatic nucleus (SCN), hypothalamus (HPOA), liver (LIV), gall bladder (GBD), brown adipose tissue (BAT), kidney (KDN), heart (HEA) and muscle (MUS), from wild-type (WT) and Per1-/-/Per2-/- (DKO) mice housed under constant darkness and ad lib...
ORGANISM(S): Mus Musculus 
2023-11-28 | PXD047352 |
ProteomicsHigh-throughput lysis and proteolytic digestion of tissues using pressure cycling technology for proteomics
we describe a protocol for pressure cycling technology (PCT) assisted tissue sample preparation for high-throughput proteomics
ORGANISM(S): Homo Sapiens Mus Musculus 
2021-12-24 | PXD030645 |
ProteomicsNCI60 proteome by PCT-SWATH - Quantitative Proteome Landscape of the NCI-60 Cancer Cell Lines
We obtained quantitative analysis of the NCI-60 cell panels using pressure cycling technology (PCT) and SWATH-MS. Each cell was analyzed in duplicate. The data were analyzed using a cell line SWATH assay library and OpenSWATH, followed by SWATH-expert refinement.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-07-29 | MSV000085848 | MassIVE
ProteomicsQuantitative proteomics reveals the inherent antibiotics resistance mechanism against norfloxacin resistance in Aeromonas hydrophlia
To construct the spectral library, 100 μg peptides from each sample were mixed and separated into 10 fractions by a RIGOL L‐3000 HPLC (Puyuanjingdian science and technology Ltd., Beijing, China). In detail, the mixture peptides were injected into a Gemini-NX C18 110A column (Size 250×4.6 mm, Particl...
ORGANISM(S): Aeromonas Hydrophila Subsp. Hydrophila Atcc 7966 
2022-09-07 | PXD036551 |
MetabolomicsGNPS - Proteomic and Metabolomic Characterization of COVID-19 Patient Sera MRMHR
Targeted mass spectrometric assays for the 22 proteins in a second test cohort containing 19 COVID-19 patients
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-05-30 | MSV000085515 | GNPS
MetabolomicsGNPS - Proteomic and Metabolomic Characterization of COVID-19 Patient Sera
Early detection and effective treatment of severe COVID-19 patients remain major challenges. Here, we performed proteomic and metabolomic profiling of sera from 46 COVID-19 and 53 control individuals. We then trained a machine learning model using proteomic and metabolomic measurements from a traini...
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 (ncbitaxon:2697049) Homo Sapiens (ncbitaxon:9606) 
2020-05-29 | MSV000085507 | GNPS
ProteomicsProteomic and Metabolomic Characterization of COVID-19 Patient Sera MRMHR
Targeted mass spectrometric assays for the 22 proteins in a second test cohort containing 19 COVID-19 patients
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-05-30 | MSV000085515 | MassIVE
ProteomicsProteomic and Metabolomic Characterization of COVID-19 Patient Sera
Early detection and effective treatment of severe COVID-19 patients remain major challenges. Here, we performed proteomic and metabolomic profiling of sera from 46 COVID-19 and 53 control individuals. We then trained a machine learning model using proteomic and metabolomic measurements from a traini...
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 (ncbitaxon:2697049) Homo Sapiens (ncbitaxon:9606) 
2020-05-29 | MSV000085507 | MassIVE
ProteomicsAberrant NAD+ metabolism underlies Zika virus-induced microcephaly
ZIKV-infection during pregnancy can cause microcephaly in newborns, yet the underlying mechanisms remain largely unexplored. Here, we reveal extensive and large-scale metabolic reprogramming events in ZIKV-infected mouse brains. We perform a multi-omics study comprising transcriptomics, proteomics, ...
ORGANISM(S): Mus Musculus 
2021-06-18 | PXD026814 |
ProteomicsARIH1 Signaling Promotes Anti-tumor Immunity by Targeting PD-L1 for Proteasomal Degradation
We find EGFR inhibitors promote PD-L1 ubiquitination and proteasomal degradation following GSK3α-mediated phosphorylation of Ser279/Ser283.
ORGANISM(S): Homo Sapiens 
2021-03-01 | PXD024452 |
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