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The project aims to examine the protein level changes under induced mitochondrial abasic site lesions in HeLa cells using stable isotope labeling by amino acids in cell culture (SILAC)-based quantitative proteomics. The data revealed significant changes in the expression level of several proteins. ...
ORGANISM(S): Homo sapiens (Human) 
2025-12-03 | PXD063576 | Pride
Microarray analysis was used to determine the expression profiles of lncRNAs and mRNAs between 3 pairs of earlobe keloid and normal specimens. Results provide insight into involement of lncRNAs in the pathological process of earlobe keloid formation. 3 pairs of earlobe keloid and normal specimens.
ORGANISM(S): Homo sapiens 
Deep sequencing of mRNA from Pacific oyster Crassostrea gigas Competent larvae of Crassostrea gigas were treated with epinephrine solution, and then sampled at different time intervals. For shell damage experiment, shell were broken and then tissues were sampled at different time intervals.
ORGANISM(S): Crassostrea gigas 
Proteins were extracted from fresh and intact ovarian tissues, followed by sequencing analysis
ORGANISM(S): Ovis Aries 
2026-03-28 | PXD076327 |
Dorsal and rump tissues of Gymnocypris przewalskii were taken for DIA quantitative proteomic assay analysis, comparing the two groups of proteomic data, screening the two groups of differential proteins, and providing basic data for scale development of Gymnocypris przewalskii
ORGANISM(S): Gymnocypris Przewalskii 
2023-05-13 | PXD042214 |
Extracellular vesicles (EVs) are specialized nanoscale vesicular structures that act as mediators of intercellular communication, playing crucial roles in the pathological processes of cancers. Aberrant glycosylation is a hallmark of cancer, the analysis of EVs and protein glycosylation provides val...
ORGANISM(S): Homo Sapiens 
2025-03-24 | PXD062160 |
As a first-line drug for treating advanced hepatocellular carcinoma, the resistance to sorafenib has always attracted attention. However, most attention has been focused on a series of mechanisms related to drug resistance caused after sorafenib treatment. In this study, we used proteomic techniques...
ORGANISM(S): Homo Sapiens 
2023-02-24 | PXD040371 |
Excessive deposition of extracellular matrix, mainly collagen protein, is the hallmark of organ fibrosis. The molecular mechanisms of the regulation of fibrotic protein biosynthesis are unclear. Here, we found that chemoattractant receptor homologous molecule expressed on TH2 cells (CRTH2), a cell m...
ORGANISM(S): Mus Sp. 
2021-04-25 | PXD025610 |
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