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ProteomicsA helicase-independent role of DHX15 promotes MYC stability and acute leukemia cell survival
DHX15 has been implicated in RNA splicing and ribosome biogenesis, primarily functioning as an RNA helicase. To systematically assess the cellular role of DHX15, we conducted proteomic analysis to investigate the landscape of DHX15 interactome, and identified MYC as a binding partner. DHX15 co-local...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD046692 | Pride
Protein stability Dhx15 Leukemia Myc Rna helicase 
ProteomicsProteome overview of exosome derived from plasma of cows infected with Mycobacterium bovis
Bovine tuberculosis (bTB), primarily caused by Mycobacterium bovis (M. bovis), is a globally zoonotic disease with significant economic impacts. Plasma exosomes have been extensively used for investigating disease processes and exploring biomarkers. While mass spectrometry (MS)-based proteomic analy...
ORGANISM(S): Bos Taurus 
PXD048167 |
ProteomicsCirculating Exosomes proteome of Colorectal Cancer Based on Rapid DIA-MS
Early screening is essential for the treatment of colorectal cancer (CRC). Concerns are rising regarding liquid biopsy due to its low invasiveness and reproducibility, especially when tissue samples are not available. Recent reports suggest that tumor-specific proteins may be stably expressed in exo...
ORGANISM(S): Homo Sapiens 
PXD015921 |
ProteomicsQuantitative acetylome analysis reveals histone modifications that may predict prognosis in hepatitis B-related hepatocellular carcinoma
Lysine acetylation (Kac) as an important post-translational modification of histone is essential for gene expression regulation in hepatocellular carcinoma (HCC), however the atlas of whole acetylated proteins for HCC tissue and the difference of protein acetylation between human normal and HCC tiss...
ORGANISM(S): Homo Sapiens 
2020-10-24 | PXD022161 |
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