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TranscriptomicsGene expression signatures for murine alveolar type II lung epithelial cells after tumor bearing
To determine the influence of primary tumors on pre-metastatic lungs, we have employed whole genome microarray expression profiling as a discovery platform to identify gene signatures of alveolar type II epithelial cells (AT-II) in TLR3 deficient mice (Tlr3-/-) and wide-type (WT) littermates with tu...
ORGANISM(S): Mus musculus 
2016-08-10 | E-GEOD-76397 | biostudies-arrayexpress
TranscriptomicsGene expression signatures for primary tumor and tumor-derived exosomes
To determine the different gene signatures between primary tumor and tumor-derived exosomes, we have employed RNA-sequencing as a discovery platform to identify gene signatures of tumor-derived exosomes, taking the original tumors as a control. We subcutaneously inoculated C57BL/6 mice with Lewis lu...
ORGANISM(S): Mus musculus 
2016-08-10 | E-GEOD-80678 | biostudies-arrayexpress
TranscriptomicsDC-specific lincRNA controls dendritic cell development and function through interacting with STAT3
To identify the functional non-coding RNAs in human DC development, we explored the gene expression profiles during DC development from peripheral monocytes. Using microarray technique, we identified many annotated lncRNAs with markedly altered expressions during human DC differentiation and maturat...
ORGANISM(S): Homo sapiens 
2014-05-02 | E-GEOD-54143 | biostudies-arrayexpress
ProteomicsIdentification of proteins associated with IFN-γR2 in macrophages
Department of Immunology & Center for Immunotherapy
ORGANISM(S): Mus Musculus 
2018-10-25 | PXD011572 |
TranscriptomicsGenomic expression analysis of human monocyte-derived DCs and monocytes
To identify the functional non-coding RNAs in human DC development, we explored the gene expression profiles during DC development from peripheral monocytes. Using RNA-seq, we identified many annotated lncRNAs with markedly altered expressions during human DC differentiation and maturation. RNA samp...
ORGANISM(S): Homo sapiens 
2014-05-02 | E-GEOD-54401 | biostudies-arrayexpress
ProteomicsThe effects of enzalutamide on androgen-dependent and androgen-independent prostate cancer cells.
To investigate the mechanisms of drug resistance and castration resistance in prostate cancer, we performed proteomic sequencing on androgen-dependent prostate cancer cells (LNCaP) and androgen-independent cells (AI) treated with enzalutamide.
ORGANISM(S): Homo Sapiens 
2024-11-26 | PXD058261 |
ProteomicsStudy of biological function of VRK1 in the development and progress of prostate cancer
VRK1 plays a significant role in the growth and drug resistance of prostate cancer.
ORGANISM(S): Homo Sapiens 
2024-11-22 | PXD058205 |
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