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ProteomicsThe sequence of Fully Synthetic peptides, Phosphorylated Tau181, Tau217, and Tau231 Calibrators, have been confirmed by MALDI-ISD analysis
We designed novel calibrators that include three phosphorylated Tau sites: Tau (1-22)-pT231, Tau (1-22)-pT217, and Tau (1-22)-pT181, respectively. Our synthesized peptides have various advantages compared with GSK3β-phosphorylated Tau-441. The novel fully synthesized calibrators not only improved th...
ORGANISM(S): Homo Sapiens 
2023-11-24 | PXD047248 |
ProteomicsProteomics of lung adenocarcinoma, parapneumonic and tuberculous pleural effusion
To investigate the proteomic and metabolomic profiles of benign and malignant pleural effusions (BPE and MPE), samples were collected from patients in the Department of Respiratory Medicine. The diagnostic confirmation for MPE relied on pleural fluid cytology, thoracoscopy, and pleural biopsy. For t...
ORGANISM(S): Homo Sapiens 
2025-12-03 | PXD071511 |
ProteomicsMetabolomics of lung adenocarcinoma, parapneumonic and tuberculous pleural effusion
To investigate the proteomic and metabolomic profiles of benign and malignant pleural effusions (BPE and MPE), samples were collected from patients in the Department of Respiratory Medicine. The diagnostic confirmation for MPE relied on pleural fluid cytology, thoracoscopy, and pleural biopsy. For t...
ORGANISM(S): Homo Sapiens 
2025-12-03 | PXD071514 |
ProteomicsCirculating Exosomes proteome of Colorectal Cancer Based on Rapid DIA-MS
Early screening is essential for the treatment of colorectal cancer (CRC). Concerns are rising regarding liquid biopsy due to its low invasiveness and reproducibility, especially when tissue samples are not available. Recent reports suggest that tumor-specific proteins may be stably expressed in exo...
ORGANISM(S): Homo Sapiens 
2019-10-20 | PXD015921 |
ProteomicsArtificial intelligence defines protein-based classification of thyroid nodules
We applied PCT-DIA on a total of 1161 nodules from 1133 patients using either tissue cores (1 mm diameter; 0.5–1 mm depth) punched from regions of interest marked on retrospective FFPE tissue blocks or prospective cytology specimens from FNA aspirates. The samples comprise (i) a discovery set of FFP...
ORGANISM(S): Homo Sapiens 
2022-09-07 | PXD036554 |
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