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ProteomicsProteomics of bacterial and ovarian cancer ascites extracellular vesicles
Extracellular vesicles (EVs) are present in body fluids, and they can be disease biomarkers. Emerging evidence has proven that EVs are released not only from mammalian cells but also from bacteria. Ovarian cancer has a dismal prognosis because of difficulties in early detection. This study aimed to ...
ORGANISM(S): Lactobacillus Gasseri (ncbitaxon:1596) 
2025-02-23 | MSV000097198 | MassIVE
TranscriptomicsTranscription profiling of mouse wild-type and B cell-specific TAK1-deficient B cells to elucidate how TAK1 regulates BCR-mediated proliferative response
BCR-induced gene expression profile in wild-type and B cell-specific TAK1-deficient B cells; to elucidate how TAK1 regulates BCR-mediated proliferative response Experiment Overall Design: Purified splenic B cells (CD43 negative) were treated with or without anti-IgM (20 micloG/mL) for 4 h. Total RNA...
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-3065 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse wild-type, TBK1, IKKi(Ikbke), or TBK1 IKKi doubly deficient embryonic fibroblats to elucidate how TBK1 and/or IKKi mediates B-DNA-mediated innate immune responses
B-DNA-induced gene expression profile in wild-type, TBK1, IKKi(Ikbke), or TBK1 IKKi doubly deficient embryonic fibroblats; to elucidate how TBK1 and/or IKKi mediates B-DNA-mediated innate immune responses. Experiment Overall Design: Total RNA was extracted from embryonic fibroblats transfected for 4...
ORGANISM(S): Mus musculus 
2007-12-07 | E-GEOD-4171 | biostudies-arrayexpress
UnknownRegulation of hematopoiesis by the K63-specific ubiquitin-conjugating enzyme Ubc13.
Not available
S-EPMC2791607 | biostudies-literature
TranscriptomicsTranscription profiling of mouse Trib1-deficient animals vs controls
The purpose of this experiment was to compare the gene expression pattern between wild-type and Trib1-deficient macrophages in response to LPS. Experiment Overall Design: Two samples to define LPS-inducible gene and 4 samples (2 for wild-type and the rests for Trib1-deficient mice) for comparison.
ORGANISM(S): Mus musculus 
2008-11-06 | E-GEOD-8788 | biostudies-arrayexpress
GenomicsNrf2 bindng in C2C12 myotubes
Nrf2 (NF-E2-related-factor-2) contributes to the maintenance of glucose homeostasis in vivo. Nrf2 suppresses blood glucose levels by protecting pancreatic β-cells from oxidative stress and improving peripheral tissue glucose utilization. To elucidate the molecular mechanisms by which Nrf2 contribut...
ORGANISM(S): Mus musculus 
2016-04-06 | E-GEOD-78780 | biostudies-arrayexpress
TranscriptomicsIdentification of a novel risk factor for intracranial aneurysms in ADPKD using iPSC models
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2016-08-04 | E-GEOD-74453 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis nst1-1 nst3-1 mutants
Wood is one of the most important and enormous biomass that is widely used in our life. It is formed by successive addition of secondary xylem that develops continuously from cambium. The transcriptome of nst1 nst3 “double-knockout” lines was examined to know the effect of mutations on wood form...
ORGANISM(S): Arabidopsis thaliana 
2008-06-13 | E-GEOD-5187 | biostudies-arrayexpress
Genomicsena-DATASET-NIG-07-03-2016-14:49:59:413-12 - samples
We performed target re-sequencing for 1.29 Mb interval of chromosome 9 (chr9:21299764–22590271, hg19). NimbleGen SeqCap EZ choice system was used as a target enrichment method (Roche Diagnostics). A DNA probe set complementary to the target region was designed by NimbleDesign. The libraries were seq...
EGAD00001001942 | EGA
GenomicsSearching for variants associated with endometriosis
We explored regulatory mechanism of a SNP on chromosome 9p21 associated with endometriosis by leveraging “allele-specific” functional genomic approaches. By re-sequencing 1.29 Mb of 9p21 region and scrutinizing DNase-seq data from the ENCODE project, we prioritized rs17761446 as a candidate function...
EGAS00001001741 | EGA
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