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ProteomicsLC-MS/M of GABARAPL1 and GABARAPL1Y49A/L50A immunoprecipitates
To identify substrates or adaptors of selective autophagy, we performed a differential interactome screen using wild-type GABARAPL1 and the LIR-docking site mutant GABARAPL1Y49A/N50A,
ORGANISM(S): Homo sapiens (Human) 
2021-04-09 | PXD024290 | Pride
Gabarapl1 Hek293t cells 
ProteomicsLC-MS/MS analysis of FLAG-NEK9 immunoprecipitates
Immunoprecipitates of FLAG-NEK9 was analyzed to detect interacting proteins under serum starvation conditions.
ORGANISM(S): Mus musculus (Mouse) 
2021-04-09 | PXD024292 | Pride
Mouse Mouse embryonic fibroblast 
TranscriptomicsGSTP1 expression predicts poor pathological complete response to neoadjuvant chemotherapy in ER-negative breast cancer
The purpose of the present study was to investigate the association of glutathione S-transferase P1 (GSTP1) expression with resistance to neoadjuvant paclitaxel followed by 5-fluorouracil/epirubicin/cyclophosphamide (P-FEC) in human breast cancers. The relationship of GSTP1 expression and GSTP1 prom...
ORGANISM(S): Homo sapiens 
2012-03-20 | E-GEOD-32646 | biostudies-arrayexpress
GenomicsPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [RRBS]
We report a reprogrammable mouse system in which reprogramming factor expression in vivo can be controlled temporally by treatment with doxycycline (Dox). Transient expression of reprogramming factors in vivo results in tumor development in various tissues, consisting of undifferentiated dysplastic...
ORGANISM(S): Mus musculus 
2014-02-13 | E-GEOD-52303 | biostudies-arrayexpress
TranscriptomicsPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
We report a reprogrammable mouse system in which reprogramming factor expression in vivo can be controlled temporally by treatment with doxycycline (Dox). Transient expression of reprogramming factors in vivo results in tumor development in various tissues, consisting of undifferentiated dysplastic...
ORGANISM(S): Mus musculus 
2014-02-13 | E-GEOD-51786 | biostudies-arrayexpress
TranscriptomicsDifferent levels of canonical Wnt signaling exert distinct roles in the colonic epithelium
There is a gradient of M-NM-2-catenin expression along the colonic crypt axis with the highest levels at the crypt bottom. However, it remains unclear whether different levels of canonical Wnt signaling exert distinct roles in the colonic epithelium. In the present study, we first showed that the ca...
ORGANISM(S): Mus musculus 
2013-01-22 | E-GEOD-41688 | biostudies-arrayexpress
TranscriptomicsAnalysis of small RNAs in piRNA pathway mutant mouse testes
Piwi-interacting RNAs are 25-32 nt small RNAs bound to Piwi proteins. To know the steps where factors involved in the piRNA biogenesis (MILI, MIWI2, ZUC (MitoPLD), MVH) work, we sequenced small RNAs from mutant mouse testes and analyzed piRNAs. Examination of small RNAs in testes of mutant mouse
ORGANISM(S): Mus musculus 
2010-05-27 | E-GEOD-20327 | biostudies-arrayexpress
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