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ProteomicsThe disturbance of lipid metabolism by the TNF-α /PLEKHA5/FCRLA axis leads to the proliferation, invasion and metastasis of cutaneous malignant melanoma
Background: Cutaneous malignant melanoma (CMM) is one of the most highly fatal cancers; its pathogenesis requires study. We recognize that abnormalities in lipid metabolism may be associated with the risk of CMM development; nevertheless, the role of lipid metabolism in the proliferation, invasion, ...
ORGANISM(S): Homo Sapiens 
2024-08-12 | PXD054835 |
UnknownTBL1X and Flot2 form a positive feedback loop to promote metastasis in nasopharyngeal carcinoma.
Not available
S-EPMC8771836 | biostudies-literature
UnknownExploring research trends and hotspots on PCSK9 inhibitor studies: a bibliometric and visual analysis spanning 2007 to 2023.
Not available
S-EPMC11621103 | biostudies-literature
UnknownLipoprotein(a) and Benefit of PCSK9 Inhibition in Patients With Nominally Controlled LDL Cholesterol.
Not available
S-EPMC8822604 | biostudies-literature
UnknownSafety of the PCSK9 inhibitor alirocumab: insights from 47 296 patient-years of observation.
Not available
S-EPMC11249957 | biostudies-literature
ProteomicsMetabolomic profiling reveals 5-Hydroxylysine and 1-Methylnicotinamide are metabolic indicators of keloid severity
Metabolomic profiling reveals 5-Hydroxylysine and 1-Methylnicotinamide are metabolic indicators of keloid severity
ORGANISM(S): Homo Sapiens 
2022-03-08 | PXD032290 |
GenomicsFacilitates chromatin transcription complex is a marker and target of aggressive cancers with lower survival rates
The Facilitates Chromatin Transcription (FACT) is involved in chromatin remodeling during transcription, replication and DNA repair and is considered to be an ubiquitously expressed complex that has no known associations with any disease. However, we discovered that FACT is expressed in very limited...
ORGANISM(S): Homo sapiens 
2013-03-22 | E-GEOD-45393 | biostudies-arrayexpress
TranscriptomicsRNA duplex map in living cells reveals higher order transcriptome structure
RNA has the intrinsic property to base pair, forming complex structures fundamental to its diverse functions. Here we develop PARIS, a method based on reversible psoralen-crosslinking for global mapping of RNA duplexes with near base-pair resolution in living cells. PARIS analysis in three human and...
ORGANISM(S): Mus musculus 
2016-04-04 | E-GEOD-74353 | biostudies-arrayexpress
UnknownPlasma Proteomics to Identify Drug Targets for Ischemic Heart Disease.
Not available
S-EPMC10641761 | biostudies-literature
ProteomicsMaternal immune activation perturbs intestinal niche through microbial glycerophospholipids and drives offspring behavioral abnormalities
Using a mouse MIA model induced by prenatal exposure to Toxoplasma gondii soluble tachyzoite antigen (STAg), we reveal that maternal gut dysbiosis, characterized by increased Firmicutes and Actinobacteria, drives offspring behavioral deficits. This dysbiosis disrupts intestinal barrier integrity and...
ORGANISM(S): Mus Musculus 
2026-03-04 | PXD075246 |
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