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ProteomicsSrc heterodimerically activates Lyn or Fyn to serve as targets for esophageal squamous cell carcinoma (ESCC) diagnosis and treatment
we combined phosphoproteomics and several cellular and molecular biologic strategies to identify that Src specifically interacted with the members of Src-family kinases (SFKs), such as Fyn or Lyn to form heterodimers, and subsequently phosphorylate the tyrosine sites in SH2 and kinase domains, which...
ORGANISM(S): Homo Sapiens 
2022-03-15 | PXD032306 |
ProteomicsProteome-wide identification lncRNA CCAT1 directly binding proteins by RAP-MS
We purify and identify CCAT1 binding proteins by RAP-MS. As a result, we identified out more than 600 CCAT1 binding proteins and more than 60% of them are RNA binding proteins recorded by RBPs database EuRBPDB. Among the identified CCAT1 binding proteins, Vimentin is a crucial protein. Additionally,...
ORGANISM(S): Homo Sapiens 
2020-11-26 | PXD022774 |
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