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UnknownEvaluation of a trauma-informed care (TIC) training program across community health centers in Texas: a qualitative study.
Not available
S-EPMC11545729 | biostudies-literature
TranscriptomicsGene expression profiling of in vitro derived induced and natural FOXP3+ regulatory T cells and ex-iTreg cells in the mouse
Induced Treg (iTreg) cells are essential for tolerance and can be used therapeutically, yet their stability in vivo and mechanisms of suppression are unresolved. Here, we used a treatment model of colitis to examine the role of autologous IL-10 in iTreg cell function. Mice treated with IL-10+/+ iTr...
ORGANISM(S): Mus musculus 
2012-12-06 | E-GEOD-35543 | biostudies-arrayexpress
TranscriptomicsDksA Guards Elongating RNA Polymerase Against Ribosome-Stalling-Induced Arrest
In bacteria, translation-transcription coupling inhibits RNA polymerase (RNAP) stalling. We present evidence suggesting that, upon amino acid starvation, inactive ribosomes promote rather than inhibit RNAP stalling. We developed an algorithm to evaluate genome-wide polymerase progression independent...
ORGANISM(S): Escherichia coli 
2014-04-21 | E-GEOD-54669 | biostudies-arrayexpress
TranscriptomicsExpression profiling of secreted and cell surface genes of 5 transformed cell lines and derivative xenograft tumors
Since the early stages of tumorigenesis involve adhesion, escape from immune surveillance, vascularization and angiogenesis, we devised a strategy to study the expression profiles of all publicly known and putative secreted and cell surface genes. We designed a custom oligonucleotide microarray cont...
ORGANISM(S): Homo sapiens 
2010-06-10 | E-GEOD-2179 | biostudies-arrayexpress
ProteomicsImplantation-on-a-chip cellular proteome
We have designed an implantation-on-a-chip device to model the invasion of specialized fetal extravillous trophoblasts (EVTs) from an implanting embryo into the maternal decidua. We profiled the cellular proteome of sorted EVTs or endothelial cells from devices containing different cell compositions...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-01-12 | MSV000088677 | MassIVE
ProteomicsProteomics of a microphysiological model of human trophoblast invasion during early embryo implantation
We have designed an implantation-on-a-chip device to model the invasion of specialized fetal extravillous trophoblasts (EVTs) from an implanting embryo into the maternal decidua. We profiled the proteome of the external factors secreted in the model, containing different cell population compositions...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-02-16 | MSV000086888 | MassIVE
GenomicsGenetic and Functional Drivers of Diffuse Large B Cell Lymphoma
Diffuse large B cell lymphoma (DLBCL) is the most common hematologic malignancy and is characterized by a striking degree of heterogeneity. We enrolled a total of 1001 DLBCL patients and comprehensively defined the landscape of genetic mutations, copy number alterations and expression through whole-...
EGAS00001002606 | EGA
MetabolomicsGNPS - Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target
The genomic landscape of colorectal cancer (CRC) is shaped by inactivating mutations in tumour suppressors such as APC, and oncogenic mutations such as mutant KRAS. Here we used genetically engineered mouse models (GEMMs), and multimodal mass spectrometry-based metabolomics to study the impact of co...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2023-07-18 | MSV000092468 | GNPS
ProteomicsMetabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target
The genomic landscape of colorectal cancer (CRC) is shaped by inactivating mutations in tumour suppressors such as APC, and oncogenic mutations such as mutant KRAS. Here we used genetically engineered mouse models (GEMMs), and multimodal mass spectrometry-based metabolomics to study the impact of co...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2023-07-18 | MSV000092468 | MassIVE
UnknownDexamethasone in Hospitalized Patients with Covid-19.
Not available
S-EPMC7383595 | biostudies-literature
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