Sort   by:  
 Page size 
MetabolomicsRegulatory T cells promote endurance exercise adaptation by shielding muscle mitochondria from damage

Exercise enhances physical performance and reduces the risk of many disorders such as cardiovascular disease, type 2 diabetes, dementia and cancer. Exercise characteristically incites an inflammatory response, notably in skeletal muscles. While some effector mechanisms have been identified, regul...

2023-10-10 | MTBLS8391 | MetaboLights
GenomicsTranscription factor Achaete-Scute homologue 2 initiates T follicular helper cell development [ChIP-Seq]
In immune responses, activated T cells migrate to B cell follicles and develop to T follicular helper (Tfh) cells, a new subset of CD4+ T cells specialized in providing help to B lymphocytes in the induction of germinal centers 1-3. Although Bcl6 has been shown to be essential in Tfh cell function, ...
ORGANISM(S): Mus musculus 
2014-01-01 | E-GEOD-52839 | biostudies-arrayexpress
GenomicsGlobal Mapping of H3K4me1 and H3K4me3 in human CD4+CD25+FOXP3+ Treg cells
Regulatory T cells (Treg) contribute to the crucial immunological processes of self-tolerance and immune homeostasis. However, the mechanisms underlying Treg function and cell fate decisions to differentiate between Treg and conventional T cells (Tconv) remain to be fully elucidated, especially at t...
ORGANISM(S): Homo sapiens 
2011-01-31 | E-GEOD-26427 | biostudies-arrayexpress
UnknownTGF-β1 is associated with deficits in cognition and cerebral cortical thickness in first-episode schizophrenia.
Not available
S-EPMC9259382 | biostudies-literature
TranscriptomicsBcl6 expression specifies the T follicular helper cell program in vivo
T follicular helper (Tfh) cells play a pivotal role in germinal center reactions, which requires Bcl6 transcription factor. To analyze their relationships with other effector T cell lineages and their stability in vivo, we developed and analyzed a new Bcl6 reporter mouse alone or together with other...
ORGANISM(S): Mus musculus 
2012-09-17 | E-GEOD-40068 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human acute myelogenous leukemia stem cells reveals disregulated gene networks
We performed the first genome-wide expression analysis directly comparing the expression profile of highly enriched normal human hematopoietic stem cells (HSC) and leukemic stem cells (LSC) from patients with acute myeloid leukemia (AML). Comparing the expression signature of normal HSC to that of L...
ORGANISM(S): Homo sapiens 
2009-08-12 | E-GEOD-17054 | biostudies-arrayexpress
UnknownMesenchymal stem cell-based tissue regeneration is governed by recipient T lymphocytes via IFN-γ and TNF-α.
Not available
S-EPMC3233650 | biostudies-literature
UnknownMagnesium-Phenolic Nanoeditor Refining Gliomatous T Cells for Metalloimmunotherapy.
Not available
S-EPMC11752515 | biostudies-literature
UnknownRegulatory T Cells in Autoimmune Hepatitis: Unveiling Their Roles in Mouse Models and Patients.
Not available
S-EPMC7575771 | biostudies-literature
UnknownProteomic analysis revealed T cell hyporesponsiveness induced by Haemonchus contortus excretory and secretory proteins.
Not available
S-EPMC7222441 | biostudies-literature
Sort   by:  
 Page size