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UnknownLocalized DNA tetrahedrons assisted catalytic hairpin assembly for the rapid and sensitive profiling of small extracellular vesicle-associated microRNAs.
Not available
S-EPMC9714172 | biostudies-literature
MetabolomicsTheabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism
Pu-erh tea displays cholesterol-lowering properties, but the underlying mechanism has not been elucidated. Theabrownin is one of the most active and abundant pigments in Pu-erh tea. Here, we show that theabrownin alters the gut microbiota in mice and humans, predominantly suppressing microbes associ...
2021-11-18 | MTBLS1259 | MetaboLights
MetabolomicsAge-, sex- and proximal-distal-resolved multi-omics identifies regulators of intestinal aging in non-human primates.

The incidence of intestinal diseases increases with age, but the regulators of gut aging and the molecules linking gut aging and diseases remain largely unknown. By profiling the transcriptome, proteome, phosphoproteome and metabolome of 104 Macaca fascicularis large intestinal tissues, ...

2023-12-14 | MTBLS7612 | MetaboLights
ProteomicsProteome of extracellular vesicles derived from breast cancer cells
MDA-MB-231 cells were irradiated with 10 Gy X-rays and the medium was harvest for extracellular vesicles isolation 24 hours post-irradiation. Proteins carrying by EVs of irradiated and control cells were then analysed by LC-MS.
ORGANISM(S): Homo Sapiens 
2024-04-22 | PXD051650 |
GenomicsGenome-wide chromatin-immunoprecipitation studies of purified SAN cells reveals critical direct targets of ISL1 and suggests potential co-factor families for ISL1 action in SAN cells
Understanding factors that drive development and function of the sinoatrial node (SAN) is crucial to development of potential therapies for sinus arrhythmias, including potential generation of biological pacemakers. Here, we identify a key cell autonomous role for the LIM homeodomain transcription f...
ORGANISM(S): Mus musculus 
2015-07-23 | E-GEOD-68974 | biostudies-arrayexpress
ProteomicsLncRNA-Smad7 mediates cross-talk between Nodal/TGF-β and BMP signaling to regulate cell fate determination of pluripotent and multipotent cells
LC-MS/MS combined with the ChIRP for the mESCs of WT and lncRNA-Smad7 KO
ORGANISM(S): Mus musculus (Mouse) 
2023-03-10 | PXD036394 | Pride
Mouse lc-ms/ms mescs chirp 
ProteomicsPotential binding proteins of CAV3 obtained from LC-MS/MS
To gain further insight into the molecular mechanisms of CAV3 in DCM. we conducted liouid chromatography-tandem mass spectrometry (LC-MS/MSassays to identify potential binding proteins of CAV3 in cardiomyocytes.LC-MS/MS was conducted by SpecAly Life Technology Co, Ltd. (Wuhan, China).
ORGANISM(S): Homo Sapiens 
2023-08-21 | PXD044674 |
ProteomicsIdentification of ubiquitination sites on the GSTM2 protein
The human GSTM2 protein was enriched, followed by mass spectrometry to identify its ubiquitination sites.
ORGANISM(S): Homo Sapiens 
2025-12-15 | PXD071988 |
ProteomicsNovel integrated trace sample preparation unraveled the proteome transformation during mesenchymal-amoeboid transition
This is a novel sample preparation for proteomic analysis of rare cells
ORGANISM(S): Homo Sapiens Mus Musculus 
2021-07-03 | PXD027085 |
ProteomicsProteome analysis of spermathecal fluid and seminal plasma reveals the mechanism of sperm storage in Amphioctopus fangsiao
The development of males and females of the cephalopod Amphioctopus fangsiao is asyn-chronous. The male produces sperm after maturity for storage in a spermatophore prior to mating. After mating, the sperm enters the female spermatheca for storage until ovulation occurs, a period that lasts for 8 mo...
ORGANISM(S): Amphioctopus Fangsiao 
2025-11-20 | PXD071103 |
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