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TranscriptomicsDose-dependent dual roles of PDGF-BB–PDGFR-? in vascular remodeling and opposing effects of anti-PDGF drug-induced metastasis
Anti-PDGF agents are routinely used as a key component in front-line therapy for the treatment of various cancers. However, molecular mechanisms underlying their impact on vascular remodeling in relation to the dose issue remain poorly understood. Here we show that in high PDGF-BB-producing tumors, ...
ORGANISM(S): Mus musculus 
2013-07-22 | E-GEOD-46564 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP6.0 array data for different clinical outcomes of HBV infection
Chronic hepatitis B virus (HBV) infection is a serious global public health problem. To identify susceptibility loci for disease progression of HBV infection, we performed this genome-wide association study using DNA pools of case and control constructed by progressed HBV carriers (acute liver failu...
ORGANISM(S): Homo sapiens 
2013-12-10 | E-GEOD-26034 | biostudies-arrayexpress
UnknownCorrelation between platelet-derived growth factor-B gene polymorphism and coronary heart disease.
Not available
S-EPMC9550974 | biostudies-literature
TranscriptomicsTranscriptomic analysis of MAPK KOs mutants under normal growing conditions (bb)
au07-10_mpk - bb - Gain insight into the function of mpk genes by characterizing the transcriptional profile of the mpk5, mpk10 and mpk11 KO mutants in comparison with that of the Arabidopsis wt plants. - Transcriptomic analysis of the double mutant bak1-4 bkk1-1 to compare its gene expression profi...
ORGANISM(S): Arabidopsis thaliana 
2009-10-30 | E-GEOD-18748 | biostudies-arrayexpress
UnknownEssential role for OspA/B in the life cycle of the Lyme disease spirochete.
Not available
S-EPMC2213294 | biostudies-literature
UnknownQuantitative proteomic analysis of gastric cancer tissue reveals novel proteins in platelet-derived growth factor b signaling pathway.
Not available
S-EPMC5400646 | biostudies-literature
TranscriptomicsApplication of SNP microarrays to the genome-wide analysis of chromosomal instability in premalignant airway lesions
Chromosomal instability is central to the process of carcinogenesis. The detection of somatic chromosomal alterations in small premalignant lesions genome-wide remains challenging since sample heterogeneity dilutes the aberrant cell information. We introduced an analytic metric termed "delta-θ&...
ORGANISM(S): Homo sapiens 
2014-03-07 | E-GEOD-43168 | biostudies-arrayexpress
UnknownThe platelet derived growth factor-B polymorphism is associated with risk of severe fever with thrombocytopenia syndrome in Chinese individuals.
Not available
S-EPMC5078099 | biostudies-literature
UnknownDocking-based structural splicing and reassembly strategy to develop novel deazapurine derivatives as potent B-RafV600E inhibitors.
Not available
S-EPMC5519245 | biostudies-literature
UnknownRegioselective B(3,4)-H arylation of o-carboranes by weak amide coordination at room temperature.
Not available
S-EPMC8162305 | biostudies-literature
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