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TranscriptomicsTranscription profiling of human normal human bronchial epithelial (NHBE) cells exposed to whole cigarette smoke over a time series to study the impact of tobacco exposure
Gene expression patterns were assessed in normal human bronchial epithelial (NHBE) cells exposed to cigarette smoke (CS) from a typical "full flavor" American brand of cigarettes in order to develop a better understanding of the genomic impact of tobacco exposure, which can ultimately define biomark...
ORGANISM(S): Homo sapiens 
2008-04-06 | E-GEOD-10718 | biostudies-arrayexpress
UnknownSLCO2B1 and SLCO1B3 may determine time to progression for patients receiving androgen deprivation therapy for prostate cancer.
Not available
S-EPMC3138634 | biostudies-literature
TranscriptomicsTranscription profiling of mouse innate immune response of nasal-associated lymphoid tissue (NALT) to Streptococcus pyogenes infection.
Streptococcus pyogenes is a major causative agent of tonsillitis or pharyngitis in children, which can lead to more invasive infections and noninfectious sequellae. S. pyogenes can persist in tonsils, while one-third of children treated with antibiotics continue to shed streptococci and have recurre...
ORGANISM(S): Mus musculus 
2009-07-11 | E-GEOD-11494 | biostudies-arrayexpress
UnknownThe chemotherapy-induced senescence-associated secretome promotes cell detachment and metastatic dissemination through metabolic reprogramming.
Not available
S-EPMC13472910 | biostudies-literature
GenomicsLoss of PHF20 does not negatively affect deposition of H4K16 acetylation, but does impact the expression of MOF targets
Protein post-translational modifications transmit signals in part by creating binding sites for effector molecules. This is especially true in epigenetic pathways where histone tails are heavily modified, resulting in the recruitment of molecules that can affect transcription. One such molecule, pla...
ORGANISM(S): Mus musculus 
2012-02-27 | E-GEOD-29306 | biostudies-arrayexpress
TranscriptomicsCanonical NF-kB Activation is Essential for Epstein-Barr Virus Latent Membrane Protein 1 TES2/CTAR2 Gene Regulation.
Epstein-Barr Virus (EBV) Latent Membrane Protein 1 (LMP1) transforms rodent fibroblasts and is expressed in most EBV-associated malignancies. LMP1 Transformation Effector Site 2 (TES2)/C-Terminal Activation Region 2 (CTAR2) activates NF-kappaB, p38, JNK, ERK and IRF7 pathways. We have investigated L...
ORGANISM(S): Homo sapiens 
2011-05-15 | E-GEOD-29297 | biostudies-arrayexpress
UnknownNew gene functions in megakaryopoiesis and platelet formation.
Not available
S-EPMC3335296 | biostudies-literature
UnknownWhole genome sequence analyses of brain imaging measures in the Framingham Study.
Not available
S-EPMC5772158 | biostudies-literature
UnknownPlasma AR Alterations and Timing of Intensified Hormone Treatment for Prostate Cancer: the STAMPEDE Phase 3 Randomized Clinical Trial.
Not available
S-EPMC11869088 | biostudies-literature
UnknownMetformin for patients with metastatic prostate cancer starting androgen deprivation therapy: a randomised phase 3 trial of the STAMPEDE platform protocol.
Not available
S-EPMC12303861 | biostudies-literature
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