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TranscriptomicsA library of yeast transcription factor motifs
The sequence specificity of DNA-binding proteins is the primary mechanism by which the cell recognizes genomic features. Here, we describe systematic determination of yeast transcription factor DNA-binding specificities. We obtained binding specificities for 112 DNA-binding proteins representing 19 ...
ORGANISM(S): Saccharomyces cerevisiae 
2008-12-26 | E-GEOD-12349 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of liver, kidney and brain from male and female Zebra Finches
Each array hybridization involved one male sample hybridized in competition to one female sample. For each hybridization one sample was labeled with Cy5 and the other with Cy3. Half of the male samples were labeled with Cy5 and rest with Cy3. Each hybridization was tissue-specific (i.e., hybridiz...
ORGANISM(S): Taeniopygia guttata 
2007-02-15 | E-MEXP-543 | biostudies-arrayexpress
TranscriptomicsMiz1 is required to maintain physiological levels of autophagic flux_1
Mice: knock-out of the Miz1 POZ-domain in brain (Miz1DPOZNes) and control mice. The RNA expression in cerebella of of old Miz1 delta POZ mice (1.5 years), old control mice (1.5 years), young Miz1 delta POZ mice (5.5 weeks) and young control mice (5.5 weeks) was compared
ORGANISM(S): Mus musculus 
2013-10-01 | E-MEXP-3878 | biostudies-arrayexpress
UnknownThe locus coeruleus mediates behavioral flexibility.
Not available
S-EPMC9662304 | biostudies-literature
TranscriptomicsExpression data from L3 Drosophila antennal-eyediscs
Growth of the drosophila eye imaginal discs is controlled by the activation of Notch in the dorsal-ventral boundary. Overexpression in the eye disc of the Notch ligand Delta together with lola and pipsqueak from the GS(2)88A8 line induces tumoral growth. We used microarray to analyze the expression ...
ORGANISM(S): Drosophila melanogaster 
2012-02-20 | E-GEOD-35471 | biostudies-arrayexpress
TranscriptomicsMiz1 is required to maintain autophagic flux_2
To isolate neuronal progenitor cells (NPCs), forebrains of E13.5 Miz1+/+ or Miz1-delta-POZ embryos were cut in small pieces, digested with trypsin and filtered through sterile gauze. Cells were cultivated in 2:1 DMEM/F12 supplemented with 1xB27 (Life technologies), 20 ng/ul EGF (Biomol), 20 ng/?l ba...
ORGANISM(S): Mus musculus 
2013-10-01 | E-MEXP-3883 | biostudies-arrayexpress
ProteomicsProteomic analysis of Adnp mutant mice
We report age-differential synaptic plasticity deficits associated with cognitive inflexibility and CaMKIIa hyperactivity in Adnp-mutant mice. These mice show impaired and inflexible contextual learning and memory additional to social and anxiety-related deficits in adults long after a marked decrea...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
MSV000090257 | MassIVE
TranscriptomicsTranscription profiling of chicken male and female embryonic livers (arnol-affy-chick-445002)
The study is relevant to an understanding of the forces that lead to sex differences in the brain. Many neural and psychiatric diseases affect men and women differently, so the understanding of sex differences in brain function impacts on our understanding of why the male and female brain differ in ...
ORGANISM(S): Gallus gallus 
2008-11-08 | E-GEOD-6856 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of chicken male and female embryonic brains (arnol-affy-chick-345142)
The study is relevant to an understanding of the forces that lead to sex differences in the brain. Many neural and psychiatric diseases affect men and women differently, so the understanding of sex differences in brain function impacts on our understanding of why the male and female brain differ in...
ORGANISM(S): Gallus gallus 
2008-11-08 | E-GEOD-6844 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of chicken male and female embryonic hearts (arnol-affy-chick-445639)
The study is relevant to an understanding of the forces that lead to sex differences in the brain and other somatic tissues. Many neural and psychiatric diseases affect men and women differently, so the understanding of sex differences in brain function impacts on our understanding of why the male a...
ORGANISM(S): Gallus gallus 
2008-11-08 | E-GEOD-6843 | biostudies-arrayexpress
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