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Genomicsgut metagenome
gut metagenome Raw sequence reads
PRJNA577929 | ENA
TranscriptomicsMyeloid cells are enriched in tonsillar crypts providing insight into the host tropism of HPV
Viruses are the second leading cause of cancer worldwide, and human papillomavirus (HPV)-associated head and neck cancers are increasing in incidence in the United States. HPV preferentially infects the crypts of the tonsils rather than the surface epithelium. The present study sought to characteriz...
ORGANISM(S): Homo sapiens 
2021-06-18 | GSE155139 | GEO
TranscriptomicsTranscription profiling of Emiliania huxleyi after 6, 12 and 24 hours of viral infection infected with the virus EhV-86 in comparison to an unifected culture
Gene expression analysis of Emiliania huxleyi after 6, 12 and 24 hours of viral infection infected with the virus EhV-86 in comparison to an unifected culture.
ORGANISM(S): Emiliania huxleyi 
2009-12-01 | E-MEXP-2382 | biostudies-arrayexpress
TranscriptomicsStreptococcus mutans UA159 vs. spx mutant strains
Transcriptional profiling to investigate the regulatory roles of SpxA and SpxB of S. mutans. RNA was extracted from four replicate samples of each strain of interest (spxA mutant, spxB mutant, spxAB double-mutant, UA159 wild type) and labeled with Cy3. For each replicate, labeled RNA was hybridized...
ORGANISM(S): Streptococcus mutans 
2010-05-16 | E-GEOD-19656 | biostudies-arrayexpress
TranscriptomicsFrequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours
Inflammatory hepatocellular adenomas (IHCA) are benign liver tumours defined by the presence of inflammatory infiltrates and by the elevated expression of inflammatory proteins in tumour hepatocytes1,2. Here we show a striking activation of the IL6 signalling pathway in this tumour type, and sequenc...
ORGANISM(S): Homo sapiens 
2008-12-24 | E-GEOD-11819 | biostudies-arrayexpress
ProteomicsTumour mtDNA mutations drive aerobic glycolysis to enhance checkpoint blockade (part 2)
Mitochondrial DNA (mtDNA) encodes essential machinery for respiration and metabolic homeostasis but is paradoxically among the most common targets of somatic mutations in the cancer genome, with truncating mutations in complex I genes being over-represented1 . While mtDNA mutations have been associ...
ORGANISM(S): Mus musculus (Mouse) 
2023-11-08 | PXD044987 | Pride
Melanoma Cancer Complex i Mitochondrial dna 
TranscriptomicsMeHg exposure zebrafish embryos vs control
Gene respons in the central nervous system of zebrafish embryos exposed to the neurotoxicant methyl mercury Two-condition experiment, control vs MeHg exposure embryos (60 µg/l), Biological replicates: 4, dye swaps
ORGANISM(S): Danio rerio 
2012-05-14 | E-GEOD-37970 | biostudies-arrayexpress
GenomicsMyeloid cells are enriched in tonsillar crypts providing insight into the host tropism of HPV
Myeloid cells are enriched in tonsillar crypts providing insight into the host tropism of HPV
PRJNA648831 | ENA
ProteomicsExtended multiplexing of TMT labeling reveals age and high fat diet specific proteome changes in mouse epididymal adipose tissue
Age-related and/or high caloric intake driven changes in visceral adipose tissue contribute to the development of diabetes and cardiovascular disease. The lack of reliable, high-throughput methods to analyze the adipose tissue protein composition has limited our understanding of the protein network...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2018-07-03 | MSV000082569 | MassIVE
TranscriptomicsPrognostic signature of epithelial-mesenchymal transition in breast cancer
Epithelial-mesenchymal transition (EMT), a switch of polarized epithelial cells to a migratory, fibroblastoid phenotype, is considered a key process driving tumor cell invasiveness and metastasis. Using breast cancer cell lines as a model system, we sought to discover gene-expression signatures of ...
ORGANISM(S): Homo sapiens 
2010-04-11 | E-GEOD-13915 | biostudies-arrayexpress
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