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MetabolomicsMetabolic and gut microbial remodeling in captive Amur tigers under uniform feeding

Ultra-high-performance liquid chromatography (UHPLC) was conducted using a Vanquish UHPLC system (Thermo Fisher), coupled with a Q Exactive™ HF/Q Exactive™ HF-X mass spectrometer for liquid chromatography-mass spectrometry (LC-MS) analysis. To ensure...

2026-06-05 | MTBLS14159 | MetaboLights
UnknownAnnotation of cell types (ACT): a convenient web server for cell type annotation.

Background

The advancement of single-cell sequencing has progressed our ability to solve biological questions. Cell type annotation is of vital importance to this process, allowing for the analysis and interpretation of enormous single-cell datasets. At present, however, manual cell annotati...
S-EPMC10623726 | biostudies-literature
ProteomicsMass spectrometry analysis of SlLhcb2
Mass spectrometry analysis of the ΔLhcb2 protein after a 2-hour incubation with GNAT2.
ORGANISM(S): Solanum lycopersicum 
2025-08-25 | PXD054007 | Pride
Tomato lhcb2 lc_ms 
UnknownCombined homologous recombination repair deficiency and immune activation analysis for predicting intensified responses of anthracycline, cyclophosphamide and taxane chemotherapy in triple-negative breast cancer.

Background

Triple-negative breast cancer (TNBC) is a clinically aggressive disease with abundant variants that cause homologous recombination repair deficiency (HRD). Whether TNBC patients with HRD are sensitive to anthracycline, cyclophosphamide and taxane (ACT), and whether the combination...
S-EPMC8408988 | biostudies-literature
ProteomicsMass Spectrometry Proteomics Reveals Cell Density Affects Drug Treatment Efficacy
using proteomic data to explain the difference induced by cultured cell confluence
ORGANISM(S): Homo Sapiens 
2022-08-18 | PXD036142 |
ProteomicsMulti-omics study for drug resistance investigation
Palbociclib is a specific CDK4/6 inhibitor that has been widely applied in multiple tumor types. Different from cytotoxic drugs, the anticancer mechanism of palbociclib mainly depends on cell cycle inhibition. Therefore, the resistance mechanism is different. For clinical cancer patients, drug resis...
ORGANISM(S): Homo Sapiens 
2022-11-30 | PXD038509 |
ProteomicsLC-MS/MS Analysis of the glycosylation of human SIDT1 and SIDT2
We performed a systematic characterization of site-specific N-glycosylation and the corresponding N-glycans of human SIDT1 and SIDT2 using LC-MS/MS.
ORGANISM(S): Homo Sapiens 
PXD043824 |
ProteomicsComparative Analysis of Soybean Seed Proteome Based on Different Mass Spectrometry Acquisition Strategies
This study established a soybean seed proteome database and analyzed the raw mass spectrometry data of BoxCar and DIA on MaxQuant based on this database. Subsequently, the three mass spectrometry acquisition strategies, DDA, DIA and BoxCar, were compared for their depth of protein identification, da...
ORGANISM(S): Glycine Max 
PXD052278 |
ProteomicsArginine GlcNAcylation of Rab small GTPases by the pathogen Salmonella Typhimurium
We determined the GlcNAcyaltion of Rab1 by a Salmonella T3SS effector SseK3. IP experiments were performed from HEK293 cells and MS files were acquired on Q Exactive mass spectrometer. We analysed the differences of protein abundance, comparing the normalized intensity on distinct proteins from diff...
ORGANISM(S): Homo Sapiens Escherichia Coli Mus Musculus 
PXD019062 |
ProteomicsMass-spectroscopic quantification of CHAC1-regulated protein cysteine S-glutathionylation
S-glutathionylation is an important post-translational modification of a cysteine residue of target protein. We applied a quantitative redox proteomics approach to identify the specific cysteine residues as targets of S-glutathionylation. Using this approach, we profiled CHAC1-associated changes in ...
ORGANISM(S): Mus Musculus 
2024-03-12 | PXD050569 |
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