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MetabolomicsSalmonella Typhimurium reprograms macrophage metabolism via T3SS effector SopE2 to promote intracellular replication and virulence

Salmonella Typhimurium establishes systemic infection by replicating in host macrophages. Here we show that macrophages infected with S. Typhimurium exhibit upregulated glycolysis and decreased serine synthesis, leading to accumulation of glycolytic intermediates. The effects on...

2024-05-22 | MTBLS2347 | MetaboLights
UnknownApplication of a next-generation sequencing (NGS) panel in newborn screening efficiently identifies inborn disorders of neonates.
Not available
S-EPMC8862216 | biostudies-literature
UnknownCharge-mediated directed assembly of Pt nanoshell on PDA: colorimetric-catalytic co-enhanced lateral flow immunoassay for point-of-care testing.
Not available
S-EPMC12683860 | biostudies-literature
MetabolomicsIdentification of AK4 and RHOC as novel oncogenes addicted by adult T-cell leukemia
Adult T-cell leukemia (ATL) is a highly aggressive T-cell malignancy characterized by human T-cell leukemia virus type 1 (HTLV-1) infection. ATL has a very poor prognosis and lacks satisfactory treatments; therefore, it is critical to identify novel targets in ATL cells in order to develop effective...
2025-02-03 | MTBLS11844 | MetaboLights
MetabolomicsIdentification of AK4 and RHOC as novel oncogenes addicted by adult T-cell leukemia
Adult T-cell leukemia (ATL) is a highly aggressive T-cell malignancy characterized by human T-cell leukemia virus type 1 (HTLV-1) infection. ATL has a very poor prognosis and lacks satisfactory treatments; therefore, it is critical to identify novel targets in ATL cells in order to develop effective...
2025-02-03 | MTBLS11858 | MetaboLights
ProteomicsQuantitative phosphoproteomics explain cryopreservation-induced reductions in ram sperm motility
Our objective was to use quantitative phosphoproteomics for systematic comparative analyses of fresh versus frozen-thawed sperm to identify factors causing cryo-injury.
ORGANISM(S): Ovis Aries 
2023-12-28 | PXD048166 |
ProteomicsAstrocyte, OPC, OL in rat postnatal development
Proteomic analysis of astrocyte, OPC, OL isolated from postnatal day 5 rat.
ORGANISM(S): Rattus Norvegicus 
2022-05-03 | PXD033729 |
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