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UnknownEsketamine attenuates traumatic brain injury by modulating STAT3-mediated Glycolysis and immune responses.
Not available
S-EPMC11889827 | biostudies-literature
ProteomicsComprehensive multi-omics analysis revealed WEE1 as a synergistic lethal target with hyperthermia through CDK super-activation
The role of hyperthermic intraperitoneal chemotherapy (HIPEC) in epithelial ovarian cancer (EOC) is still controversial partly because of the poorly understood mechanism of action. Further an understanding of the underlying mechanisms could identify potential combination therapies. Here, we conduct ...
ORGANISM(S): Homo sapiens (Human) 
2023-12-12 | PXD040849 | Pride
Wee1 Hyperthermia Multi-omics Cdk1 Ovarian cancer Azd1775 
ProteomicsAmyotrophic Lateral Sclerosis-associated Mutants of SOD1 Modulate miRNA Biogenesis through Aberrant Interactions with Exportin 5
Mutations in SOD1 (Superoxide Dismutase 1) gene are associated with amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. By employing ascorbate peroxidase (APEX)-based proximity labeling, coupled with LC-MS/MS analysis, we uncovered 37 and 28 proteins exhibiting higher abundance i...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2024-01-26 | PXD035452 | Pride
Lc-ms affinity purification sod1 apex 
UnknownAcetyl-CoA acyltransferase 2 palmitoylation drives liver fibrosis by inducing hepatic stellate cell ferroptosis.
Not available
S-EPMC12859212 | biostudies-literature
ProteomicsParabacteroides distasonis-Derived Outer Membrane Vesicles Enhance Antitumor Immunity in Colon Cancer by Modulating CXCL10 and CD8+ T Cells
Outer membrane vesicles of Parabacteroides distasonis
ORGANISM(S): Parabacteroides Distasonis Atcc 8503 
2024-04-15 | PXD051464 |
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