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ProteomicsMass Spectrometry-based Profiling of GALNT1-associated Protein Complexes Isolated via Co-Immunoprecipitation
This project identifies GALNT1-interacting proteins in primary fibroblast-like synoviocytes (RASFs) derived from rheumatoid arthritis patients using co-immunoprecipitation (co-IP) coupled with mass spectrometry (MS). Briefly, RASF lysates were incubated with anti-GALNT1 antibody to capture GALNT1-a...
ORGANISM(S): Homo Sapiens 
2025-12-08 | PXD071709 |
MetabolomicsGABA regulates IL-1β production in macrophages
Neurotransmitters have been well-documented to determine immune cell fates; however, whether and how γ-amino butyric acid (GABA) shapes the function of innate immune cells is still obscure. Here, we demonstrated that GABA orchestrates macrophage maturation and inflammation. GABA treatment during mac...
2023-01-31 | MTBLS6337 | MetaboLights
ProteomicsQuantitative proteomics analysis reveals XDH related with ovarian oxidative stress in-volved in broodiness of geese
In this study, we screened the key proteins through the detection of antioxidant level of ovary combined with proteomic analysis to reveal the mechanism of goose broodiness and provide a new perspective to enhance the egg production performance.
ORGANISM(S): Anser Cygnoides Orientalis 
2024-08-26 | PXD055319 |
ProteomicsCDK5RAP3, a UFL1 substrate adaptor, is critical for liver development
Protein modification by ubiquitin and ubiquitin-like proteins (UBLs) regulates numerous biological functions. The UFM1 system, a novel UBL conjugation system, is implicated in mouse development and hematopoiesis. However, its broad biological functions and working mechanisms remain largely elusive. ...
ORGANISM(S): Mus Musculus 
2019-01-14 | PXD012340 |
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