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ProteomicsGlobal Analysis of Lysine Acetylation in the Brain Cortex of K18-hACE2 Mice Infected with SARS-CoV-2
In order to research the relationship between neurological sequelae of COVID-19 and acetylation of brain cortexes, we reported for the first time the acetylome in the brain cortex of the K18-hACE2 infected mouse model, and the difference between the SARS-CoV-2 infection group and the control group, ...
ORGANISM(S): Mus Musculus 
2022-09-20 | PXD036853 |
ProteomicsProteomic and phosphoproteomic profiling of original, Delta, or Omicron strain SARS-CoV-2-infected lung of rhesus macaque
The Omicron variant, mutated from the original SARS-CoV-2 strain, is still circulating worldwide. We performed LC-MS based proteome and phosphoproteome analysis using lung tissues separated from rhesus monkeys, which were infected with Omicron, the original virus or one of the VOCs, the Delta varian...
ORGANISM(S): Macaca Mulatta 
2023-12-12 | PXD047779 |
ProteomicsGlobal profiling of the proteome and acetylome in mice with abdominal aortic aneurysms
Abdominal Aortic Aneurysm (AAA) is a fatal vascular disease characterized by abnormal expansion of the arterial wall and a high risk of rupture. Current treatments for AAA primarily rely on surgical intervention, while effective pharmacological therapies have yet to be developed. The major bottlenec...
ORGANISM(S): Mus Musculus 
2025-02-17 | PXD060895 |
ProteomicsA comprehensive proteome and phosphoproteome atlas across nine organs of the Chinese hamster
We present the first comprehensive proteomic and phosphoproteomic atlas of nine major organs of the Chinese hamster (Cricetulus griseus). A total of 14,219 proteins, 11,828 phosphorylated proteins, and 47,122 phosphorylation sites were identified, revealing distinct inter-organ molecular features.
ORGANISM(S): Cricetulus Griseus 
2025-10-04 | PXD069241 |
ProteomicsProteomic analysis of 442 clinical plasma samples from healthy donors and COVID-19 covalescent patients
In this study, we collected plasma samples from 22 healthy controls (HC group), 43 hospitalized patients (HO group), 196 convalescent patients 6 months after COVID-19 infection (first follow-up, F1 group), and 181 convalescent patients 12 months after COVID-19 infection (second follow-up, F2 group)....
ORGANISM(S): Homo Sapiens 
2024-08-02 | PXD054533 |
ProteomicsComprehensive analysis of individual variation in the urinary proteome revealed significant gender differences
To elucidate the individual variation and related factors influencing the urinary proteome, we comprehensively analyzed the urine samples from healthy adult donors (aged 20-69 years). Co-expression network analysis revealed protein clusters representing the metabolic status, gender-related differenc...
ORGANISM(S): Homo Sapiens 
2019-05-21 | PXD013949 |
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