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UnknownA conformationally mobile cysteine residue (Cys-561) modulates Na+ and H+ activation of human CNT3.
Not available
S-EPMC3259814 | biostudies-literature
UnknownNucleobase transport by human equilibrative nucleoside transporter 1 (hENT1).
Not available
S-EPMC3173155 | biostudies-literature
ProteomicsThe colitis risk gene C1orf106 (ROCS) regulates epithelial adherens junction stability
Mohanan V, Nakata T, Desch N, L�vesque C, Boroughs A, Guzman G, Cao Z, Creasey E, Yao J, Boucher G, Charron G, Bhan AK, Schenone M, Carr SA, Reinecker HC, Daly MJ, Rioux JD, Lassen KG, Xavier RJ. Science 2018. Single nucleotide polymorphisms in C1orf106 are associated with increased risk of inflamma...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-01-16 | MSV000081941 | MassIVE
MetabolomicsUPLC-Q-TOF/MS-Based Plasma and Urine Metabolomics Contribute to the Diagnosis of Sepsis
In this study, we aimed to identify potential metabolic biomarkers that can improve the diagnostic accuracy of sepsis. Sixty-six patients including 30 septic and 36 nonsepsis patients from an intensive care unit were recruited. The global plasma and urine metabolomic profiles were determined by ultr...
2023-04-18 | MTBLS3505 | MetaboLights
UnknownA Novel Aerobic Degradation Pathway for Thiobencarb Is Initiated by the TmoAB Two-Component Flavin Mononucleotide-Dependent Monooxygenase System in Acidovorax sp. Strain T1.
Not available
S-EPMC5691415 | biostudies-literature
ProteomicsIdentification of protein interaction partners of the lncRNA Lassie
The shear stress-regulated lncRNA LASSIE interferes with endothelial cell function as knockdown of Lassie affects apoptosis, proliferation and angiogenic sprouting in vitro. RNA-antisense purification and subsequent mass spectrometry analysis identifed junctional proteins (such as PECAM-1) as intera...
ORGANISM(S): Homo sapiens (Human) 
2021-07-22 | PXD018724 | Pride
Rna/protein interaction 
ProteomicsIdentification of VE-cadherin associated proteins regulated through the lncRNA LASSIE
The shear stress-regulated lncRNA LASSIE interacts with cytoskeletal proteins as shown by RNA-antisense purification and subsequent mass spectrometry analysis using an anti-LASSIE and a non-targeting 3’ Desthiobiotin-TEG labeled 2’ O-Me-RNA. As this analysis resulted in high protein binding to the n...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD018734 | Pride
Rna/protein interaction 
ProteomicsVE-cadherin associated proteins in the absence of lncRNA LASSIE
The shear stress-regulated lncRNA LASSIE interacts with junctional proteins (e.g. PECAM-1, which interacts with VE-cadherin) and influences endothelial barrier function. Here we characterize the remodeling of the VE-Cadherin complex by the lncRNA LASSIE. LASSIE silenced HUVECs were subjected to co-i...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD018725 | Pride
Rna/protein interaction 
TranscriptomicsGene expression in wild type and mENT1 knock out mice
To investigate the functional importance of a nucleoside transporter, the mENT1 (Slc29a1) was knocked out in mice. The gene expression profile was compared between wildtype and mENT1 knock out mice in two tissues. RNA was isolated from heart and kidney from 3 mENT1 knockout and 3 wildtype (FVB/N) mi...
ORGANISM(S): Mus musculus 
2011-04-27 | E-GEOD-22565 | biostudies-arrayexpress
UnknownEmulating the GRADE trial using real world data: retrospective comparative effectiveness study.
Not available
S-EPMC9527635 | biostudies-literature
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