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ProteomicsQuantitative proteomics investigation of total protein and acetylated 4D Label free of 18 samples from H9C2 cells
The quantitative investigation of acetylated proteomics was carried out in this project. To ensure high reliability of the results, we filtered the identification data using a criterion of localization probability>0.75. This study identified a total of 9755 acetylation sites located on 3051 proteins...
ORGANISM(S): Rattus Norvegicus 
2023-06-16 | PXD043035 |
ProteomicsLow-dose metformin targets the lysosome-AMPK pathway through PEN2
Metformin is the most prescribed anti-diabetic medicine, and has also been shown to have other various benefits, such as anti-aging and anti-cancer effects. For clinical doses of metformin, it is known that AMPK plays a major role; however, the direct molecular target of metformin remains unclear. H...
ORGANISM(S): Homo Sapiens Mus Musculus 
2021-12-01 | PXD030090 |
ProteomicsAMPK targets PDZD8 to promote carbon source shift to glutamine
This project contains the raw MS data that identified PDZD8 as a substrate of AMPK on the MAM of ER-mitochondria contact. They also revealed that site T527 is an AMPK-phosphorylation site.
ORGANISM(S): Mus Musculus 
2023-04-06 | PXD041428 |
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