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UnknownIntegrating Network Pharmacology and Metabolomics Study on Anti-rheumatic Mechanisms and Antagonistic Effects Against Methotrexate-Induced Toxicity of Qing-Luo-Yin.
Not available
S-EPMC6305420 | biostudies-literature
ProteomicsTherapeutic targeting nudix hydrolase 1 creates a MYC-driven metabolic vulnerability
Tumor cells must rewire nucleotide synthesis to satisfy the demands of unbridled proliferation. Meanwhile, they exhibit augmented reactive oxygen species (ROS) production which paradoxically damages DNA and free dNTPs. How these metabolic processes are integrated to fuel tumorigenesis remains to be ...
ORGANISM(S): Homo sapiens (Human) 
2023-12-27 | PXD043444 | Pride
Myc Plk1 Nudt1 Cancer，protac 
UnknownIndole alkaloid glycosides with a 1'-(phenyl)ethyl unit from Isatis indigotica leaves.
Not available
S-EPMC7280145 | biostudies-literature
UnknownDifferentially expressed tRFs in CD5 positive relapsed & refractory diffuse large B cell lymphoma and the bioinformatic analysis for their potential clinical use.
Not available
S-EPMC6882323 | biostudies-literature
ProteomicsBlood coagulation and complement activation interact to increase disease activity in systemic lupus erythematosus and coagulation D-Dimer combined with complement C4 is a biomarker of lupus activity
This study was conducted to (1) find deregulation of certain pathways in SLE at multi-omics levels; (2) evaluate the associations among blood coagulation, complement activation, inflammatory responses and SLE disease severity; (3) develop biomarkers to facilitate better the assessment of the likelih...
ORGANISM(S): Homo sapiens (Human) 
2018-10-27 | PXD004443 | Pride
Systemic lupus erythematosus  blood coagulation itraq 
TranscriptomicsHuman transcriptome expression analysis of cervical cancer
Although many protein-coding genes have been identified to be aberrantly expressed in cervical cancer, the mechanisms of development and progression of cervical cancer remain unclear. In recent years, non-coding RNAs, especially including microRNAs and long non-coding RNAs, have been shown to play i...
ORGANISM(S): Homo sapiens 
2014-10-27 | E-GEOD-55940 | biostudies-arrayexpress
UnknownEnhanced bypass of PD-L1 translation reduces the therapeutic response to mTOR kinase inhibitors.
Not available
S-EPMC10491412 | biostudies-literature
UnknownAntidepressant-like activity, active components and related mechanism of Hemerocallis citrina Baroni extracts.
Not available
S-EPMC9469015 | biostudies-literature
UnknownHydrogen bond based smart polymer for highly selective and tunable capture of multiply phosphorylated peptides.
Not available
S-EPMC5587758 | biostudies-literature
UnknownIdentification of Differentially Expressed Long Non-coding RNAs in Polarized Macrophages.
Not available
S-EPMC4726337 | biostudies-literature
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