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MetabolomicsSpecific biomarkers for stochastic division patterns and starvation-induced quiescence under limited glucose levels in fission yeast
Glucose as a source of energy is centrally important to our understanding of life. We investigated the cell division-quiescence behavior of the fission yeast Schizosaccharomyces pombe under a wide range of glucose concentrations (0-111 mM). The mode of S. pombe cell division under a microfluidic per...
2017-07-06 | MTBLS316 | MetaboLights
ProteomicsBiotin starvation in yeast - Biotin starvation causes mitochondrial protein hyperacetylation and partial rescue by the SIRT3-like deacetylase Hst4p
yeast cells were starved for biotin and the proteome and acetylome changes were analyzed by quantitative mass spectrometry
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2016-12-13 | PXD002168 | Pride
Yeast cells starved for biotin 
TranscriptomicsTranscription profiling and proteomic profiling of Saccharomyces cerevisiae wild-type and GPA2 mutant strains
In response to limited nitrogen and abundant carbon sources, diploid Saccharomyces cerevisiae strains undergo a filamentous transition in cell growth as part of pseudohyphal differentiation. Use of the disaccharide maltose as the principal carbon source, in contrast to the preferred nutrient monosac...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-15 | E-GEOD-7820 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression analysis of Salmonella enterica serovar Enteritidis during growth in whole egg
Even though the incidence of salmonellosis in humans has decreased over the last years, Salmonella spp. are still a leading cause of foodborne outbreaks in Europe (Anon., 2014). Of more than 2500 different serovars of Salmonella enterica, S. enterica serovar Enteritidis (S. Enteritidis) is the most ...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Enteritidis 
2016-03-04 | E-MTAB-4521 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of serum starved prelamin A-accumulating hMSCs gene expression.
Analysis of serum starved prelamin A-accumulating hMSCs at gene expression level. The hypothesis tested in the present study was that prelamin A accumulation induces the dysregulation of genes that are essensial for cell survival under a stress condition such as serum starvation. The results provide...
ORGANISM(S): Homo sapiens 
2014-06-23 | E-GEOD-52563 | biostudies-arrayexpress
TranscriptomicsLongSAGE transcriptome profiling in the widespread marine coccolithophore Emiliania huxleyi
The abundant and widespread coccolithophore Emiliania huxleyi plays an important role in mediating CO2 exchange between the ocean and the atmosphere through its impact on marine photosynthesis and calcification. Here, we use long serial analysis of gene expression (SAGE) to identify E. huxleyi genes...
ORGANISM(S): Emiliania huxleyi CCMP1516 
2007-07-07 | E-GEOD-8376 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human mammary epithelial cells infected with a recombinant adenoviral vector expressing a mutated HER2 inactivated for kinase function or wild type HER2
As an oncogene, use of HER2 vaccines in humans requires the development of HER2 immunotherapies with maximal immunologic potential, but minimal oncologic potential. To address these issues, we developed a recombinant adenoviral vector expressing a mutated HER2 inactivated for kinase function (Ad-HE...
ORGANISM(S): Homo sapiens 
2008-11-22 | E-GEOD-13274 | biostudies-arrayexpress
TranscriptomicsA lack of secretory leukocyte protease inhibitor (SLPI) causes defects in granulocytic differentiation.
Expression data from CD34+ hematopoietic cells transduced with control or anti-SLPI shRNA, serum starved and treated with G-CSF. CD34+ hematopoietic cells were isolated from the bone marrow of healthy individuals, transduced with lenitvirus-based RFP-expressed shRNA constructs targeting SLPI mRNA or...
ORGANISM(S): Homo sapiens 
2014-03-04 | E-GEOD-53353 | biostudies-arrayexpress
MetabolomicsMetaboLights MTBLS316 - GNPS Specific biomarkers for stochastic division patterns and starvation-induced quiescence under limited glucose levels in fission yeast
This data set was downloaded from MetaboLights (http://www.ebi.ac.uk/metabolights/) accession number MTBLS316 Abstract:Glucose as a source of energy is centrally important to our understanding of life. We investigated the cell division-quiescence behavior of the fission yeast Schizosaccharomyces pom...
ORGANISM(S): Schizosaccharomyces Pombe 
2018-08-07 | MSV000082794 | GNPS
TranscriptomicsRapamycin effect on Wild Type and TSC deficient Mouse Embryonic Fibroblasts : Time Course
Aberrant activation of the mammalian target of rapamycin (mTOR) complex 1 (mTORC1) is a common molecular event in a large variety of pathological settings, including genetic tumor syndromes, cancer, and obesity. However, the cell intrinsic consequences of mTORC1 activation remain poorly defined. He...
ORGANISM(S): Mus musculus 
2010-07-30 | E-GEOD-21755 | biostudies-arrayexpress
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