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ProteomicsMouse PPAR gamma with/without 15-keto-PGE2
15-keto-PGE2 is proposed as an endogenous ligand of PPAR gamma. The modification of 15-keto-PGE2 can induce PPAR gamma transcriptional activation. This project aims to identify the binding site of 15-keto-PGE2 on PPAR gamma.
ORGANISM(S): Mus musculus (Mouse) 
2025-02-17 | PXD059654 | Pride
15-keto-pge2 Ppar gamma 
MetabolomicsArginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction
Defective arginine synthesis, due to the silencing of argininosuccinate synthase 1 (ASS1), is a common metabolic vulnerability in cancer, known as arginine auxotrophy. Understanding how arginine depletion kills arginine-auxotrophic cancer cells will facilitate the development of anti-cancer therapeu...
2019-11-07 | MTBLS745 | MetaboLights
UnknownDiscovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation.
Not available
S-EPMC5349910 | biostudies-literature
UnknownTemporal Trends of Acute Kidney Injury and Associated Risk Exposures in Extremely Preterm Infants.
Not available
S-EPMC8455040 | biostudies-literature
UnknownScreening for Helicobacter pylori to Prevent Gastric Cancer: A Pragmatic Randomized Clinical Trial.
Not available
S-EPMC11581485 | biostudies-literature
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