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MetabolomicsThe trans-omics landscape of COVID-19
The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency. Various omics results have been reported for COVID-19, but the molecular hallmarks of COVID-19, especially in those patients without comorbidities, have not been fully investigated. Here we collect blood samples from 2...
2021-10-06 | MTBLS2542 | MetaboLights
GenomicsSorafenib inhibits epithelial-mesenchymal transition through an epigenetic-based mechanism in human lung epithelial cells
The epithelial to mesenchymal transition (EMT) has been well recognized for many decades as an essential early step in the progression of primary tumors towards metastases. Widespread epigenetic reprogramming of DNA and histone modifications tightly regulates gene expression and cellular activity du...
ORGANISM(S): Homo sapiens 
2012-10-11 | E-GEOD-41479 | biostudies-arrayexpress
TranscriptomicsAberrantly expressed lncRNAs in Primary Varicose Great Saphenous Veins
LncRNAs are key regulatory molecules involved in a variety of biological process and human diseases. However, the pathological effects of lncRNAs on primary varicose great saphenous veins (GSVs) remain unclear. In this study, we aimed at identifying aberrantly expressed lncRNAs involved in the preva...
ORGANISM(S): Homo sapiens 
2013-10-01 | E-GEOD-51260 | biostudies-arrayexpress
ProteomicsTime course treatment with Palmitate and thapsigargin of insulinoma INS-1E cells
Time course treatment with 0.4 mM Palmitate and 200 nM thapsigargin of insulinoma INS-1E cells. Timepoints; 0, 4, 16 and 24h in biological duplicates within an iTRAQ 8 set for palmitate and thapsigargin, respectively.
ORGANISM(S): Rattus Rattus (black Rat) 
2020-08-18 | PXD020851 | JPOST Repository
TranscriptomicsA robust single primate neuroepithelial cell clonal expansion system for neural tube development and disease studies
Developing a model of primate neural tube (NT) development is important to promote many NT disorder studies in model organisms. Here, we report a robust and stable system to allow for clonal expansion of single monkey neuroepithelial stem cells (NESCs) to develop into miniature NT-like structures. S...
ORGANISM(S): Macaca mulatta 
2015-11-21 | E-GEOD-73892 | biostudies-arrayexpress
ProteomicsModified Sanjia Powder Ameliorates Cognitive Impairment and Exerts Neuroprotective Effects in 5×FAD Mice: Insights from Quantitative Proteomics
Proteomics reveals Sanjia neuroprotection mechanisms
ORGANISM(S): Mus Musculus 
2025-12-26 | PXD072435 |
ProteomicsUrinary proteome and metabolome uncover tumor microenvironment and cellular metabolism changes of renal clear cell carcinoma
We applied LC-MS to profile the urine proteome and metabolome of 314 ccRCC, 341 healthy control and 49 kidney benign disease enrolled from three cohorts to a great depth. Functionally, we revealed significant changes of extracellular matrix (ECM) organization, complement and coagulation cascades, am...
ORGANISM(S): Homo Sapiens 
2025-05-22 | PXD064183 |
ProteomicsIdentification of candidate microRNA biomarkers of endometriosis in different bodily fluids
Endometriosis is a common gynecological condition that affects approximately 10% of women of reproductive age and up to half of those experiencing infertility. However, there is a lack of reliable noninvasive diagnostic tools for diagnosing endometriosis. This study aims to identify novel biomarkers...
ORGANISM(S): Homo Sapiens 
2025-11-17 | PXD070868 |
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